Crosson B, Hughes C W
Irene Walter Johnson Rehabilitation Institute, Washington University Medical Center, St. Louis, MO 63110.
Schizophr Bull. 1987;13(4):605-21. doi: 10.1093/schbul/13.4.605.
Crosson (1985) proposed a model for language production which integrated cortical with subcortical functions. The implications of this model for schizophrenia are explored. One conclusion is that neural systems, as opposed to a single neural focus, account for schizophrenic symptoms. In this light, data regarding dysfunction in the limbic system, nucleus accumbens, globus pallidus, and prefrontal cortex, which are often seen as contradictory, can be viewed as complementary. Another conclusion is that Crosson's model may have implications specific to schizophrenic thought disorder. Random triggering of semantic segments and inability to maintain contextual referents are discussed in the context of the language production theory.
克罗森（1985年）提出了一个语言生成模型，该模型整合了皮质和皮质下功能。本文探讨了该模型对精神分裂症的影响。一个结论是，导致精神分裂症症状的是神经系统，而非单一的神经焦点。据此，有关边缘系统、伏隔核、苍白球和前额叶皮质功能障碍的数据，尽管常常看似相互矛盾，但可以被视为互补的。另一个结论是，克罗森的模型可能对精神分裂症思维障碍具有特定影响。本文在语言生成理论的背景下讨论了语义片段的随机触发以及无法维持上下文指代的问题。
