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基于磁敏感加权成像技术评估反映髋关节形态角度测量值的价值。

Value of susceptibility-weighted imaging for the assessment of angle measurements reflecting hip morphology.

机构信息

Department of Radiology, Charité, Charitéplatz 1, 10117, Berlin, Germany.

Department of Radiology, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.

出版信息

Sci Rep. 2020 Dec 1;10(1):20899. doi: 10.1038/s41598-020-77671-1.

DOI:10.1038/s41598-020-77671-1
PMID:33262372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7708417/
Abstract

Radiographs are the clinical first line imaging modality for evaluating hip morphology and pathology. MRI offers additional information and is the method of choice to evaluate soft tissue, bone marrow and preradiographic signs of osteoarthritis. Radiographs are used to measure the most morphometric parameters. The aim of this study was to compare susceptibility weighted MRI (SWMR) with radiographs to evaluate hip morphology. 40 Patients were examined with standard MR-sequences, coronal SWMR and radiographs in anteroposterior pelvic view. Coronal maximum intensity projection (MIP) images of both hips were automatically reconstructed on SWMR and T1weighted images. Sharp´s angle, Tönnis angle, lateral center-edge angle of Wiberg and caput-collum-diaphyseal angle were measured on coronal SWMR MIP-images, T1weighted MIP-images and radiographs. Measurements were compared by linear regression analysis and Bland-Altmann Plots, using radiographs as reference standard. Additionally, a ratio between the signal intensity of muscles and bone on SWMR and T1weighted MIP-images was calculated and compared between these two sequences. SWMR enables the reliable assessment of Sharp´s angle (SWMR: R = 0.80; T1weighted: R = 0.37), Tönnis angle (SWMR: R = 0.86; T1weighted: not measurable), lateral center-edge angle of Wiberg (SWMR: R = 0.88; T1weighted: R = 0.40) and caput-collum-diaphyseal angle (SWMR: R = 0.38; T1weighted: R = 0.18) compared to radiographs with a higher accuracy than conventional MR imaging. The ratio between the intensity of muscles and bone was significant higher on SWMR (2.00 and 2.02) than on T1weighted MIP-images (1.6 and 1.42; p < 0.001).

摘要

放射学是评估髋关节形态和病变的临床一线影像学方法。MRI 提供了额外的信息,是评估软组织、骨髓和影像学前骨关节炎的首选方法。放射学用于测量大多数形态学参数。本研究旨在比较磁共振敏感加权成像 (SWMR) 与放射学评估髋关节形态。40 例患者接受标准 MR 序列、冠状位 SWMR 和前后位骨盆 X 线检查。在 SWMR 和 T1 加权图像上自动重建双侧髋关节冠状位最大强度投影 (MIP) 图像。在冠状位 SWMR MIP 图像、T1 加权 MIP 图像和 X 线片上测量 Sharp 角、Tönnis 角、Wiberg 外侧中心边缘角和股骨头颈干角。使用放射学作为参考标准,通过线性回归分析和 Bland-Altman 图比较测量值。此外,还计算了 SWMR 和 T1 加权 MIP 图像上肌肉和骨骼信号强度之间的比值,并比较了这两种序列之间的比值。SWMR 能够可靠地评估 Sharp 角(SWMR:R=0.80;T1 加权:R=0.37)、Tönnis 角(SWMR:R=0.86;T1 加权:不可测量)、Wiberg 外侧中心边缘角(SWMR:R=0.88;T1 加权:R=0.40)和股骨头颈干角(SWMR:R=0.38;T1 加权:R=0.18),与放射学相比,准确性更高。SWMR 上肌肉和骨骼之间的强度比值明显高于 T1 加权 MIP 图像(2.00 和 2.02)(1.6 和 1.42;p<0.001)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f18a/7708417/5a12490721b2/41598_2020_77671_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f18a/7708417/bc460c9c6f21/41598_2020_77671_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f18a/7708417/f4a22cde0286/41598_2020_77671_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f18a/7708417/ea71bc1ed44f/41598_2020_77671_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f18a/7708417/5374372fceb0/41598_2020_77671_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f18a/7708417/5a12490721b2/41598_2020_77671_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f18a/7708417/bc460c9c6f21/41598_2020_77671_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f18a/7708417/f4a22cde0286/41598_2020_77671_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f18a/7708417/ea71bc1ed44f/41598_2020_77671_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f18a/7708417/5374372fceb0/41598_2020_77671_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f18a/7708417/5a12490721b2/41598_2020_77671_Fig5_HTML.jpg

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