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新型冠状病毒肺炎的神经系统表现:一例报告

Neurological Manifestations of COVID-19: A Case Report.

作者信息

Malekmohammad Majid, Hashemian Seyed Mohammad Reza, Mansourafshar Babak, Jamaati Hamidreza

机构信息

Tracheal Diseases Research Center (TDRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Chronic Respiratory Diseases Research Center, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Tanaffos. 2020 Nov;19(2):160-164.

Abstract

A novel coronavirus disease (COVID-19) was reported in Wuhan, China in December 2019 and spread rapidly around the world, causing high rates of mortality and morbidity. This disease is known for its respiratory manifestations. Also, there have been several reports of neurological involvement in patients with COVID-19. In this study, we present a 55-year-old Iranian male patient, who was referred from another medical center with a decreased level of consciousness. Upon admission, only respiratory signs of COVID-19 were observed, but later, some neurological manifestations were also observed, such as an alteration in mental status, disorientation, stupor, and finally coma. In radiological studies, a hemorrhagic encephalopathy pattern was detected. Despite improved oxygenation and alleviation of respiratory symptoms with antiviral and anti-inflammatory therapies, cerebral injuries progressed, and the patient died due to severe brain damage.

摘要

2019年12月,中国武汉报告了一种新型冠状病毒病(COVID-19),该病迅速在全球传播,导致高死亡率和高发病率。这种疾病以其呼吸道表现而闻名。此外,已有多篇关于COVID-19患者神经受累的报道。在本研究中,我们介绍了一名55岁的伊朗男性患者,他从另一家医疗中心转诊而来,意识水平下降。入院时,仅观察到COVID-19的呼吸道症状,但后来也观察到一些神经学表现,如精神状态改变、定向障碍、昏迷,最终发展为昏迷。在放射学研究中,检测到出血性脑病模式。尽管通过抗病毒和抗炎治疗改善了氧合并缓解了呼吸道症状,但脑损伤仍在进展,患者因严重脑损伤死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b0d/7680512/5e847cead4bf/Tanaffos-19-160-g001.jpg

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