Jacobson Jennifer, Antony Kathleen, Beninati Michael, Alward William, Hoppe Kara K
Department of Obstetrics and Gynecology, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States of America.
Department of Pulmonology and Critical Care, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States of America.
Case Rep Womens Health. 2021 Jan;29:e00273. doi: 10.1016/j.crwh.2020.e00273. Epub 2020 Nov 25.
Severe infection with COVID-19 virus in pregnancy offers unique management challenges for the obstetrician and critical care specialist. We report the case of a woman at 26 weeks of gestation with acute respiratory distress syndrome secondary to COVID-19 infection treated with dexamethasone, remdesivir, convalescent plasma and mechanical ventilation. Cesarean delivery was performed at 29 weeks due to worsening maternal status. This case offers insight into the assessment and successful use of treatment strategies, including dexamethasone, remdesivir, convalescent plasma, early prone positioning, conservative fluid management, permissive hypoxia and low tidal volume parameters with ventilator support for pregnancies affected by severe COVID-19 infection.
妊娠期感染新型冠状病毒肺炎病毒会给产科医生和重症监护专家带来独特的管理挑战。我们报告了一例妊娠26周的女性病例,该患者因新型冠状病毒肺炎感染继发急性呼吸窘迫综合征,接受了地塞米松、瑞德西韦、康复期血浆治疗及机械通气。由于产妇病情恶化,于孕29周行剖宫产。该病例为评估和成功使用治疗策略提供了见解,这些策略包括地塞米松、瑞德西韦、康复期血浆、早期俯卧位、保守液体管理、允许性低氧血症以及在呼吸机支持下采用低潮气量参数,用于治疗受严重新型冠状病毒肺炎感染影响的妊娠患者。