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前列腺癌根治术后尿失禁和勃起功能障碍的治疗:德国癌症幸存者的护理利用不足。

Treatment of post-prostatectomy urinary incontinence and erectile dysfunction: there is insufficient utilisation of care in German cancer survivors.

机构信息

Department of Urology, TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.

Department of Health Services Research, Carl Von Ossietzky University, Ammerlaender Heerstrasse 140, 26111, Oldenburg, Germany.

出版信息

World J Urol. 2021 Aug;39(8):2929-2936. doi: 10.1007/s00345-020-03526-z. Epub 2020 Dec 1.

Abstract

PURPOSE

Treatment of post-prostatectomy urinary incontinence (UI) and erectile dysfunction (ED) increases quality of life (QoL). Aim of our study was to evaluate the utilisation of care among patients with post-prostatectomy UI and ED in Germany.

METHODS

The HAROW study documented treatment of patients with localised prostate cancer (≤ T2c) in Germany. 1260 patients underwent radical prostatectomy (RP). Patients answered validated questionnaires after a median follow-up of 6.3 years. Response rate was 76.8%.

RESULTS

Median age at RP was 65 (IQR 60-69) years. 14% (134/936) used more than one pad per day for UI. 25% (26/104, 30 missing) of UI patients underwent surgery to improve continence. Of patients without surgery, 41% (31/75) reported a moderate-to-severe issue concerning their incontinence with worse mental health and QoL. 81% (755/936) patients were unable to have an erection firm enough for sexual intercourse. Of all ED patients, 40% (319/793) used ED treatment regularly or tried it at least once. 49% (243/499) of patients with interest in sex never tried ED treatment. In multivariate analysis, patients not using ED treatments were older (≥ 70 years OR 4.1), and more often had preoperative ED (OR 2.3) and less interest in sex (OR 2.2). Nevertheless, 30% (73/240) of these patients had moderate-to-severe issues with their ED reporting worse mental health and QoL.

CONCLUSION

Almost half of the patients without post-prostatectomy UI and ED treatment reported moderate-to-severe issues with a significant decrease in QoL. This indicates an insufficient utilisation of care in Germany.

摘要

目的

治疗前列腺切除术后尿失禁(UI)和勃起功能障碍(ED)可提高生活质量(QoL)。我们的研究旨在评估德国前列腺切除术后 UI 和 ED 患者的护理利用情况。

方法

HAROW 研究记录了德国局限性前列腺癌(≤T2c)患者的治疗情况。1260 名患者接受了根治性前列腺切除术(RP)。患者在中位随访 6.3 年后回答了经过验证的问卷。应答率为 76.8%。

结果

RP 时的中位年龄为 65(IQR 60-69)岁。14%(134/936)每天使用超过一个尿垫用于 UI。25%(26/104,30 例缺失)的 UI 患者接受手术改善控尿。未手术的患者中,41%(31/75)报告其失禁问题中度至重度,心理健康和 QoL 更差。81%(755/936)的患者无法进行足够坚硬的勃起以进行性交。所有 ED 患者中,40%(319/793)定期使用 ED 治疗或至少尝试过一次。49%(243/499)有性兴趣的患者从未尝试过 ED 治疗。多变量分析显示,未使用 ED 治疗的患者年龄较大(≥70 岁 OR 4.1),术前 ED 更常见(OR 2.3),性兴趣较低(OR 2.2)。然而,这些患者中有 30%(73/240)报告其 ED 中度至重度,心理健康和 QoL 显著下降。

结论

近一半未接受前列腺切除术后 UI 和 ED 治疗的患者报告存在中度至重度问题,生活质量显著下降。这表明德国护理的利用不足。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb7c/8405514/bda5752e69a2/345_2020_3526_Fig1_HTML.jpg

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