Chang Dan, Chen Jinjin, Liu Yong, Huang Huawen, Qin Anjun, Deng Guo-Jun
Key Laboratory for Green Organic Synthesis and Application of Hunan Province, Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan 411105, China.
Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, South China University of Technology, Guangzhou 510640, China.
J Org Chem. 2021 Jan 1;86(1):110-127. doi: 10.1021/acs.joc.0c01788. Epub 2020 Dec 2.
A three-component reaction has been developed for the construction of multiaryl-substituted pyrrole derivatives from arylketones, amines, and nitrovinylarenes under metal-free conditions. Hence, homologous 1,2,4-triaryl-substituted pyrrole products were obtained in good to high yields. Furthermore, 2,3,5-triaryl-substituted pyrroles were selectively formed in the absence of nitrovinylarenes. The photophysical properties of some pyrrole products have been investigated to show good aggregation-induced emission (AIE) activity.
已经开发出一种三组分反应，用于在无金属条件下由芳基酮、胺和硝基乙烯基芳烃构建多芳基取代的吡咯衍生物。因此，以良好至高收率获得了同系的1,2,4-三芳基取代的吡咯产物。此外，在没有硝基乙烯基芳烃的情况下选择性地形成了2,3,5-三芳基取代的吡咯。已经研究了一些吡咯产物的光物理性质，以显示出良好的聚集诱导发光（AIE）活性。
