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尿道下裂患儿行尿道皮肤瘘切除术后瘘管复发的危险因素。

Risk factors for fistula recurrence after urethrocutaneous fistulectomy in children with hypospadias.

作者信息

Abdullaev Zafar, Agzamkhodjaev Saidanvar, Chung Jae Min, Lee Sang Don

机构信息

Department of Urology, Pusan National University Yangsan Hospital, Yangsan, Korea.

Department of Pediatric Urology, National Children's Medical Center, Tashkent, Uzbekistan.

出版信息

Turk J Urol. 2021 May;47(3):237-241. doi: 10.5152/tud.2020.20323. Epub 2020 Nov 30.

Abstract

OBJECTIVE

This study aimed to investigate the risk factors of fistula recurrence after primary urethrocutaneous fistulectomy in children with hypospadias.

MATERIAL AND METHODS

The study included 63 children who underwent fistulectomy for urethrocutaneous fistula (UCFs) that occurred after urethroplasty for hypospadias, between February 2009 and December 2018. The patients were divided into 2 groups: successful group 1 and failed group 2. For data analysis, we included the demographics of the patients, the details of the previous urethroplasty (the type of hypospadias and the location of the meatus after complete chordectomy), the presence of meatal stenosis or urethral stricture after urethroplasty, and the size of the UCFs. The Student t-test and the chi-square test were performed to analyze the data using the Statistical Package for Social Sciences software.

RESULTS

The overall success rate of primary urethrocutaneous fistulectomy was 81.0% (51/63 children). The most common location of a secondary fistula was the penoscrotal area 5 (41.6%). There were no statistically significant differences in age (p=0.501), weight (p=0.063), body mass index (p=0.924), history of low birth weight (p=0.454), and history of prematurity (p=0.381). The type of hypospadias (p=0.007) and urethral defect length (p=0.021) were identified as independent risk factors for failed urethrocutaneous fistulectomy. There were no statistically significant differences in meatal stenosis (p=0.431), postoperative stricture (p=0.587), fistula location (p=0.173), multiplicity (p=0.588), and fistula size (p=0.530).

CONCLUSION

The type of hypospadias and the length of the urethral defect are the significant risk factors for secondary fistula recurrence after primary urethrocutaneous fistulectomy.

摘要

目的

本研究旨在探讨尿道下裂患儿一期尿道皮肤瘘切除术后瘘管复发的危险因素。

材料与方法

本研究纳入了2009年2月至2018年12月期间因尿道下裂尿道成形术后发生尿道皮肤瘘(UCF)而接受瘘管切除术的63例患儿。将患者分为两组:成功组1和失败组2。为进行数据分析,我们纳入了患者的人口统计学资料、既往尿道成形术的详细情况(尿道下裂类型及完全离断阴茎下弯术后尿道口位置)、尿道成形术后尿道口狭窄或尿道狭窄的情况以及UCF的大小。使用社会科学统计软件包对数据进行分析,采用学生t检验和卡方检验。

结果

一期尿道皮肤瘘切除术的总体成功率为81.0%(63例患儿中的51例)。二次瘘管最常见的位置是阴茎阴囊区域5例(41.6%)。在年龄(p = 0.501)、体重(p = 0.063)、体重指数(p = 0.924)、低出生体重史(p = 0.454)和早产史(p = 0.381)方面,差异无统计学意义。尿道下裂类型(p = 0.007)和尿道缺损长度(p = 0.021)被确定为尿道皮肤瘘切除术失败的独立危险因素。在尿道口狭窄(p = 0.431)、术后狭窄(p = 0.587)、瘘管位置(p = 0.173)、多发性(p = 0.588)和瘘管大小(p = 0.530)方面,差异无统计学意义。

结论

尿道下裂类型和尿道缺损长度是一期尿道皮肤瘘切除术后二次瘘管复发的重要危险因素。

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