Bramis J P, Sloane C E, Schanzer H, Burrows L, Taub R N
Invest Urol. 1977 Sep;15(2):143-6.
The laboratory rat has been widely used as a preclinical model of renal transplantation. Surgical anastomosis of the small lumenal structures encountered requires strict adherence to basic principles of microsurgical technique. Nonfatal technical errors may adversely affect renal allograft function and influence experimental results. Experience obtained from a series of more than 600 rat renal transplants is discussed.
实验大鼠已被广泛用作肾移植的临床前模型。对所遇到的小腔结构进行手术吻合时,需要严格遵循显微外科技术的基本原则。非致命性技术失误可能会对同种异体肾移植功能产生不利影响,并影响实验结果。本文讨论了从600多例大鼠肾移植系列中获得的经验。