Oesterwitz H
Z Urol Nephrol. 1982 Jun;75(6):377-86.
Rat kidney transplantation is a frequently used model in transplantation research and experimental microsurgery. This model has been used in studies which cover most aspects of transplantation biology. Thus in many laboratories attempts was made to improve this experimental model. However, the available techniques mostly are time consuming and the methods of urinary tract reconstruction are unsatisfactory because of numerous complications. Therefore, a detailed description of the orthotopic kidney transplantation in the rat, using end-to-end anastomosis of the kidney vessels and non-splinted end-to-end anastomosis of the ureter with simultaneous bilateral nephrectomy is presented. This technique based on preliminary experiences with 34 rat kidney transplants has produced success in 32 transplants.
大鼠肾移植是移植研究和实验显微外科中常用的模型。该模型已用于涵盖移植生物学大多数方面的研究。因此,许多实验室都试图改进这个实验模型。然而,现有的技术大多耗时,且由于并发症众多,尿路重建方法并不理想。因此,本文详细描述了大鼠原位肾移植,采用肾血管端端吻合和输尿管非支撑端端吻合并同时进行双侧肾切除术。基于34例大鼠肾移植的初步经验,该技术在32例移植中取得了成功。