Graduate School of Engineering, University of Miyazaki, Miyazaki 889-2192, Japan.
Department of Neurology, Faculty of Medicine, University of Miyazaki, Miyazaki 889-2192, Japan.
Sensors (Basel). 2020 Nov 22;20(22):6684. doi: 10.3390/s20226684.
In this paper, we introduce a simple method based on image analysis and deep learning that can be used in the objective assessment and measurement of tremors. A tremor is a neurological disorder that causes involuntary and rhythmic movements in a human body part or parts. There are many types of tremors, depending on their amplitude and frequency type. Appropriate treatment is only possible when there is an accurate diagnosis. Thus, a need exists for a technique to analyze tremors. In this paper, we propose a hybrid approach using imaging technology and machine learning techniques for quantification and extraction of the parameters associated with tremors. These extracted parameters are used to classify the tremor for subsequent identification of the disease. In particular, we focus on essential tremor and cerebellar disorders by monitoring the finger-nose-finger test. First of all, test results obtained from both patients and healthy individuals are analyzed using image processing techniques. Next, data were grouped in order to determine classes of typical responses. A machine learning method using a support vector machine is used to perform an unsupervised clustering. Experimental results showed the highest internal evaluation for distribution into three clusters, which could be used to differentiate the responses of healthy subjects, patients with essential tremor and patients with cerebellar disorders.
在本文中,我们介绍了一种基于图像分析和深度学习的简单方法,可用于震颤的客观评估和测量。震颤是一种神经系统疾病,会导致人体某个或某些部位不由自主地有节奏地运动。震颤有许多类型,具体取决于其幅度和频率类型。只有进行准确的诊断,才能进行适当的治疗。因此,需要有一种分析震颤的技术。在本文中,我们提出了一种混合方法,使用成像技术和机器学习技术对与震颤相关的参数进行量化和提取。这些提取的参数用于对震颤进行分类,以便后续识别疾病。具体来说,我们通过监测指鼻试验,重点关注特发性震颤和小脑疾病。首先,使用图像处理技术分析来自患者和健康个体的测试结果。然后,对数据进行分组,以确定典型反应的类别。使用支持向量机的机器学习方法来执行无监督聚类。实验结果表明,将其分为三个聚类的内部评估最高,这可用于区分健康受试者、特发性震颤患者和小脑疾病患者的反应。