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寨卡病毒感染的小头畸形儿童中高度节律失调的识别

Identification of Hypsarrhythmia in Children with Microcephaly Infected by Zika Virus.

作者信息

Sousa Gean Carlos, Queiroz Claudio M, Sousa Patrícia, Lima Priscila, Silva Antônio Augusto Moura da, Pires Nilviane, Barros Allan Kardec

机构信息

Department of Electrical Engineering, Federal University of Maranhão (UFMA), São Luís-MA 65080-805, Brazil.

Brain Institute, Federal University of Rio Grande do Norte, Natal 59078-970, Brazil.

出版信息

Entropy (Basel). 2019 Feb 28;21(3):232. doi: 10.3390/e21030232.

DOI:10.3390/e21030232
PMID:33266947
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7514713/
Abstract

Hypsarrhythmia is an electroencephalographic pattern specific to some epileptic syndromes that affect children under one year of age. The identification of this pattern, in some cases, causes disagreements between experts, which is worrisome since an inaccurate diagnosis can bring complications to the infant. Despite the difficulties in visually identifying hypsarrhythmia, options of computerized assistance are scarce. Aiming to collaborate with the recognition of this electropathological pattern, we propose in this paper a mathematical index that can help electroencephalography experts to identify hypsarrhythmia. We performed hypothesis tests that indicated significant differences in the groups under analysis, where the -values were found to be extremely small.

摘要

高峰失律是一种特定于某些影响一岁以下儿童的癫痫综合征的脑电图模式。在某些情况下,这种模式的识别会导致专家之间的分歧,这令人担忧,因为不准确的诊断会给婴儿带来并发症。尽管在视觉上识别高峰失律存在困难,但计算机辅助选项却很少。为了协助识别这种电病理模式,我们在本文中提出了一种数学指标,该指标可以帮助脑电图专家识别高峰失律。我们进行了假设检验,结果表明在分析的组中存在显著差异,其中p值被发现极小。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/266c/7514713/c8a4852ff8f7/entropy-21-00232-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/266c/7514713/abbc8695e7e6/entropy-21-00232-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/266c/7514713/33c42297657e/entropy-21-00232-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/266c/7514713/2e034dc93127/entropy-21-00232-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/266c/7514713/7ae8eeae9a72/entropy-21-00232-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/266c/7514713/c8a4852ff8f7/entropy-21-00232-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/266c/7514713/abbc8695e7e6/entropy-21-00232-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/266c/7514713/33c42297657e/entropy-21-00232-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/266c/7514713/2e034dc93127/entropy-21-00232-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/266c/7514713/7ae8eeae9a72/entropy-21-00232-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/266c/7514713/c8a4852ff8f7/entropy-21-00232-g005.jpg

相似文献

1
Identification of Hypsarrhythmia in Children with Microcephaly Infected by Zika Virus.寨卡病毒感染的小头畸形儿童中高度节律失调的识别
Entropy (Basel). 2019 Feb 28;21(3):232. doi: 10.3390/e21030232.
2
Classification of the interictal state with hypsarrhythmia from Zika Virus Congenital Syndrome and of the ictal state from epilepsy in childhood without hypsarrhythmia in EEGs using entropy measures.使用熵测度对寨卡病毒先天性综合征伴高峰节律紊乱的发作间期状态以及儿童期脑电图无高峰节律紊乱的癫痫发作期状态进行分类。
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Longitudinal evolution of electroencephalogram (EEG): Findings over five years of follow-up in children with Zika-related microcephaly from the Microcephaly Epidemic Research Group Pediatric Cohort (2015-2020).脑电图(EEG)的纵向演变:来自寨卡相关小头畸形流行研究组儿科队列(2015-2020 年)的五年随访结果。
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Hypsarrhythmia assessment exhibits poor interrater reliability: a threat to clinical trial validity.棘慢波综合评估表现出较差的评价者间信度:对临床试验有效性的威胁。
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Epileptic Disord. 2020 Feb 1;22(1):73-82. doi: 10.1684/epd.2020.1130.

本文引用的文献

1
Sleep EEG of Microcephaly in Zika Outbreak.寨卡疫情中小头畸形的睡眠脑电图
Neurodiagn J. 2018;58(1):11-29. doi: 10.1080/21646821.2018.1428461.
2
High Amplitude Background Slow Waves in Normal Children Aged 3 to 18 Months: Implications for the Consideration of Hypsarhythmia.3至18个月正常儿童的高幅背景慢波:对痉挛样节律(高峰失律)考量的意义
J Clin Neurophysiol. 2018 Mar;35(2):151-154. doi: 10.1097/WNP.0000000000000449.
3
Long-Range Temporal Correlations Reflect Treatment Response in the Electroencephalogram of Patients with Infantile Spasms.
长程时间相关性反映婴儿痉挛症患者脑电图中的治疗反应。
Brain Topogr. 2017 Nov;30(6):810-821. doi: 10.1007/s10548-017-0588-5. Epub 2017 Sep 13.
4
Developing a novel epileptic discharge localization algorithm for electroencephalogram infantile spasms during hypsarrhythmia.为具有高度失律的婴儿痉挛症脑电图中癫痫放电定位开发一种新的算法。
Med Biol Eng Comput. 2017 Sep;55(9):1659-1668. doi: 10.1007/s11517-017-1616-z. Epub 2017 Feb 9.
5
Sleep EEG patterns in infants with congenital Zika virus syndrome.先天性寨卡病毒综合征婴儿的睡眠脑电图模式。
Clin Neurophysiol. 2017 Jan;128(1):204-214. doi: 10.1016/j.clinph.2016.11.004. Epub 2016 Nov 14.
6
Hypsarhythmia or Hypsarrhythmia?高度节律失调还是高幅失律?
Pediatr Neurol Briefs. 2015 Aug;29(8):64. doi: 10.15844/pedneurbriefs-29-8-7.
7
Automatic localization of epileptic spikes in eegs of children with infantile spasms.婴儿痉挛症患儿脑电图中癫痫棘波的自动定位
Annu Int Conf IEEE Eng Med Biol Soc. 2015;2015:6194-7. doi: 10.1109/EMBC.2015.7319807.
8
Improving the inter-rater agreement of hypsarrhythmia using a simplified EEG grading scale for children with infantile spasms.使用简化脑电图分级量表提高婴儿痉挛症患儿高峰失律的评分者间一致性。
Epilepsy Res. 2015 Oct;116:93-8. doi: 10.1016/j.eplepsyres.2015.07.008. Epub 2015 Jul 28.
9
Epileptic spasms without hypsarrhythmia in infancy and childhood: tonic spasms as a seizure type.婴幼儿期和儿童期无高峰节律紊乱的癫痫性痉挛:强直痉挛作为一种发作类型
Epileptic Disord. 2015 Jun;17(2):188-93. doi: 10.1684/epd.2015.0738.
10
Hypsarrhythmia paroxysm index: A tool for early prediction of infantile spasms.高峰失律发作指数:一种早期预测婴儿痉挛症的工具。
Epilepsy Res. 2015 Mar;111:54-60. doi: 10.1016/j.eplepsyres.2015.01.005. Epub 2015 Jan 25.