Lee Jeong Min, Jeon Young Joon, Kim Kook Young, Hwang Kyu-Yeon, Kwon Young-A, Koh Kyungmin
Department of Ophthalmology, Kim's Eye Hospital, Konyang University College of Medicine, Seoul, South Korea.
Eur J Ophthalmol. 2021 Sep;31(5):2300-2306. doi: 10.1177/1120672120969035. Epub 2020 Dec 2.
To compare the lipid layer thickness (LLT), meibomian gland (MG) dropouts, and blinking pattern determined by the analysis of images acquired from the LipiView II (LVII) and the IDRA Ocular surface analyzer.
A cross-sectional single-visit observational study was conducted. The LLT (minimum, maximum, and average), percentages of MG dropouts, and partial blink rates (PBR) were taken from both eyes of 47 participants using LVII and IDRA. Both devices were used to image the inferior eyelid of each participant in a random order.
Forty-seven participants (mean age 56.77 ± 14.47 (21-79) years, 66% female) completed the study. There was no significant difference in LLT between the two devices. A significant difference in percentages of MG dropouts was obtained between the LVII (36.51 ± 17.53) and the IDRA (45.36 ± 21.87), = 0.003). There was also a significant difference in PBR between the LVII (0.51 ± 0.37) and the IDRA (0.23 ± 0.27), < 0.001).
No significant difference in LLT was obtained between LVII and IDRA. IDRA had a significantly lesser percentage of MG dropout and a higher PBR compared to LVII. These results indicate that these devices should not be used interchangeably for the evaluation of MG dropouts and PBR.
比较通过分析从LipiView II（LVII）和IDRA眼表分析仪获取的图像所确定的脂质层厚度（LLT）、睑板腺（MG）缺失情况和眨眼模式。
进行了一项横断面单次就诊观察性研究。使用LVII和IDRA从47名参与者的双眼获取LLT（最小值、最大值和平均值）、MG缺失百分比和部分眨眼率（PBR）。两台设备以随机顺序对每位参与者的下眼睑进行成像。
47名参与者（平均年龄56.77±14.47（21 - 79）岁，66%为女性）完成了研究。两台设备之间的LLT无显著差异。LVII（36.51±17.53）和IDRA（45.36±21.87）之间的MG缺失百分比存在显著差异（P = 0.003）。LVII（0.51±0.37）和IDRA（0.23±0.27）之间的PBR也存在显著差异（P < 0.001）。
LVII和IDRA之间的LLT无显著差异。与LVII相比，IDRA的MG缺失百分比显著更低，PBR更高。这些结果表明，在评估MG缺失和PBR时，这些设备不应互换使用。
