Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China.
Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China.
BMC Pregnancy Childbirth. 2020 Dec 2;20(1):751. doi: 10.1186/s12884-020-03454-1.
Sacrococcygeal teratoma is one of the most common congenital tumors in newborns and infancy. The incidence is 1 per 20,000-40,000 live births. Ultrasonography is an optimal method for prenatal screening and diagnosis of fetal sacrococcygeal teratoma. MRI can be used to assist in the diagnosis. However, sacrococcygeal teratoma in the twin pregnancy is rare.
We reported a case of one twin with sacrococcygeal teratoma in dichorionic-diamniotic twin pregnancy.One twin with sacrococcygeal teratoma was diagnosed at the second trimester by ultrasonic examination and another twin was normal. A regular and careful antenatal care was conducted by the multidisciplinary team. The parents refused to perform the fetal MRI and examine the chromosome of both twin.At 37 + 1 of gestation, planned cesarean section was performed. The healthy male co-twin (twin A) weighed 2880 g.The male twin with SCT (twin B) weighed 2900 g, complying with 6 × 3 × 3 cm cystic and solid mass in sacrococcygeal region. At four days of age twin B underwent excisional surgery of the sacrococcygeal teratoma and coccyx and discharged 7 days after surgery. The mother and both babies were followed up and are all in good health until now.
CONCLUSION(S): Sacrococcygeal teratoma in twin pregnancy is rare. Early antenatal diagnosis is important. Once the sacrococcygeal teratoma is diagnosed, clinicians should be aware of the associated maternal and fetal complications. Expecting parents should be counseled by the multidisciplinary team about the management and prognosis of the STC twin and co-twin. Prompt surgical excision of the sacrococcygeal teratoma after birth should be suggested.
骶尾部畸胎瘤是新生儿和婴儿期最常见的先天性肿瘤之一。发病率为每 20000-40000 例活产中 1 例。超声检查是产前筛查和诊断胎儿骶尾部畸胎瘤的最佳方法。磁共振成像（MRI）可用于协助诊断。然而，双胞胎妊娠中的骶尾部畸胎瘤较为罕见。
我们报告了一例双绒毛膜-双羊膜囊双胎妊娠中一胎合并骶尾部畸胎瘤的病例。一胎通过超声检查在孕中期被诊断为骶尾部畸胎瘤，另一胎正常。多学科团队对孕妇进行了定期和仔细的产前检查。父母拒绝对胎儿进行 MRI 检查和双胎染色体检查。孕 37+1 周时，行计划性剖宫产术。健康的男同卵双胎（胎儿 A）体重 2880g，合并骶尾部 SCT 的男婴（胎儿 B）体重 2900g，骶尾部有 6×3×3cm 的囊性和实性肿块。出生后第 4 天，胎儿 B 行骶尾部畸胎瘤和尾骨切除术，术后 7 天出院。母亲和两个婴儿均随访至今，情况良好。
双胞胎妊娠中的骶尾部畸胎瘤较为罕见。早期产前诊断很重要。一旦诊断出骶尾部畸胎瘤，临床医生应意识到其与母婴相关的并发症。多学科团队应向期待父母提供关于 STC 双胎和单胎的管理和预后的咨询。建议在出生后及时行骶尾部畸胎瘤切除术。
