Gastroenterology and Endoscopy Department, Ibrahim Bin Hamad Obaid Allah Hospital, Ministry of Health and Prevention, Ras Al Khaiman, United Arab Emirates.
Department of Gastroenterology, Sheikh Shakbout Medical City, Abu Dhabi, United Arab Emirates.
World J Gastroenterol. 2020 Nov 21;26(43):6710-6769. doi: 10.3748/wjg.v26.i43.6710.
Ulcerative colitis and Crohn's disease are the main entities of inflammatory bowel disease characterized by chronic remittent inflammation of the gastrointestinal tract. The incidence and prevalence are on the rise worldwide, and the heterogeneity between patients and within individuals over time is striking. The progressive advance in our understanding of the etiopathogenesis coupled with an unprecedented increase in therapeutic options have changed the management towards evidence-based interventions by clinicians with patients. This guideline was stimulated and supported by the Emirates Gastroenterology and Hepatology Society following a systematic review and a Delphi consensus process that provided evidence- and expert opinion-based recommendations. Comprehensive up-to-date guidance is provided regarding diagnosis, evaluation of disease severity, appropriate and timely use of different investigations, choice of appropriate therapy for induction and remission phase according to disease severity, and management of main complications.
溃疡性结肠炎和克罗恩病是炎症性肠病的主要实体,其特征为胃肠道慢性缓解性炎症。该病在全球范围内的发病率和患病率呈上升趋势,且患者之间以及个体随时间的异质性非常显著。随着我们对其发病机制的理解不断深入,以及治疗选择的空前增加,临床医生在治疗患者时,已逐渐采用基于循证医学的干预措施。本指南是在阿联酋胃肠病学和肝病学会的支持下制定的,其制定过程是对相关文献进行系统回顾,并通过德尔菲共识程序提供了基于证据和专家意见的建议。本指南就疾病的诊断、严重程度的评估、不同检查的合理适时应用、根据疾病严重程度选择适当的诱导缓解期治疗方案以及主要并发症的管理等方面提供了全面且最新的指导建议。