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印度东部加尔各答市一个地区内由不止一种血清型引起的登革热爆发。

Dengue fever outbreak by more than one serotype in a municipal area of Kolkata, Eastern India.

机构信息

Division of Epidemiology, ICMR-National Institute of Cholera & Enteric Diseases, Kolkata, India.

Virus unit, ICMR-National Institute of Cholera & Enteric Diseases, Kolkata, India.

出版信息

J Vector Borne Dis. 2019 Oct-Dec;56(4):380-382. doi: 10.4103/0972-9062.302043.

DOI:10.4103/0972-9062.302043
PMID:33269740
Abstract

A dengue outbreak struck Baranagar municipality area of North 24 Parganas district, West Bengal in July 2016. This study presents the epidemiological and virology findings of this outbreak. The outbreak started from 17 July and continued until 17 December. Total 1660 dengue cases (overall attack rate: 7/1000) and two deaths (case fatality rate: 1/1000) were reported. All age groups were affected. Out of the 213 blood samples collected from probable dengue cases and tested at Virus Unit, ICMR-National Institute of Cholera & Enteric Diseases (NICED), Kolkata, 163 (76%) tested seropositive through NS1 / IgM ELISA confirming dengue infection. DENV 1 was the predominant (53%, 44/83) serotype followed by DENV 2 (23%, 19/83), DENV 4 (15.6%, 13/83), DENV 3 (8.4%,7/ 83). Coexistence of dengue and chikungunya virus infection was detected. Major presentation of the confirmed dengue cases was fever with headache (95%), followed by arthralgia, myalgia, retro-orbital pain, abdominal pain, diarrhoea, and rash. Abundance of vector breeding spaces was observed in the area. Accordingly the health authorities were suggested to conduct frequent mass awareness campaigns involving community to reduce breeding sources during pre-monsoon and monsoon months. Further, adult mosquito control measures were also suggested throughout the year and inter-departmental coordination was recommended for prevention of such outbreaks in future.

摘要

2016 年 7 月,孟加拉邦北 24 帕加纳斯区的巴兰加尔市爆发了登革热疫情。本研究介绍了此次疫情的流行病学和病毒学发现。疫情始于 7 月 17 日,一直持续到 12 月 17 日。共报告了 1660 例登革热病例(总发病率:7/1000)和 2 例死亡(病死率:1/1000)。所有年龄段的人都受到了影响。从可能的登革热病例中采集了 213 份血液样本,并在 ICMR-National Institute of Cholera & Enteric Diseases(NICED),加尔各答的病毒科进行了检测,通过 NS1/IgM ELISA 检测出 163 份(76%)血清呈阳性,证实了登革热感染。登革热病毒 1 型(53%,44/83)是主要血清型,其次是登革热病毒 2 型(23%,19/83)、登革热病毒 4 型(15.6%,13/83)、登革热病毒 3 型(8.4%,7/83)。检测到登革热和基孔肯雅热病毒感染的共存。确诊登革热病例的主要表现是发热伴头痛(95%),其次是关节痛、肌痛、眼眶后痛、腹痛、腹泻和皮疹。在该地区观察到大量的蚊子滋生地。因此,建议卫生当局在雨季前和雨季期间开展频繁的群众宣传运动,让社区参与进来,减少滋生地。此外,还建议全年采取成蚊控制措施,并建议各部门之间进行协调,以防止今后再次发生此类疫情。

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