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Generating evidence for therapeutic effects: the need for well-conducted randomized trials.

作者信息

Califf Robert M, Curtis Lesley H, Harrington Robert A, Hernandez Adrian F, Peterson Eric D

机构信息

Verily Life Sciences (Alphabet), South San Francisco, California, USA.

Stanford University School of Medicine, Stanford, California, USA.

出版信息

J Clin Invest. 2021 Jan 19;131(2). doi: 10.1172/JCI146391.

DOI:10.1172/JCI146391
PMID:33270604
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7810467/
Abstract
摘要

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J Am Coll Cardiol. 2020 Aug 4;76(5):580-589. doi: 10.1016/j.jacc.2020.05.069.
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Creating a Framework for Conducting Randomized Clinical Trials during Disease Outbreaks.创建疾病爆发期间进行随机临床试验的框架。
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Specifying a target trial prevents immortal time bias and other self-inflicted injuries in observational analyses.指定目标试验可防止观察性分析中出现不朽时间偏倚和其他自伤性偏倚。
J Clin Epidemiol. 2016 Nov;79:70-75. doi: 10.1016/j.jclinepi.2016.04.014. Epub 2016 May 27.
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A literature review on the representativeness of randomized controlled trial samples and implications for the external validity of trial results.关于随机对照试验样本代表性及其对试验结果外部有效性影响的文献综述。
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