Department of Orthoptics and Visual Science, School of Allied Health Sciences, Kitasato University, Kanagawa, Japan.
LOTTE Co., Ltd, Central Laboratory, Saitama, Japan.
Biomed Res Int. 2020 Nov 12;2020:2470473. doi: 10.1155/2020/2470473. eCollection 2020.
To investigate the effects of chewing gum and tablet candy to reduce eyestrain in healthy individuals.
A double-blinded crossover trial was conducted. Forty-six healthy individuals (23 men, 23 women) between 20 and 59 years old, feeling eyestrain, were enrolled. Each 10-year age group included 12 individuals except the 30s group, which included 10 individuals. A visual task was performed on reading material displayed on a computer screen at a fixed distance for 60 min. Gum or tablet candy of two pieces were chewed for two 15-min periods starting 15 and 45 min after starting to read. Subjects chewed gum on Day 1 and tablet candy on Day 2, and vice versa. Primary outcome is as follows: subjective eye fatigue (eye tiredness, eye heaviness, blurred vision, double vision, and eye dryness) using a visual analog scale (VAS). Secondary outcomes are as follows: subjective accommodation from near and far points of accommodation measured with a D'ACOMO, spherical equivalent refraction, and eye dryness by analyzing ring break-up time (RBUT) measured with the RT-7000 Auto Ref-Topographer.
The VAS scores of subjective eye fatigue were not significantly changed between chewing gum and tablet candy ( = 0.397 - = 0.909). Those scores of eye tiredness and eye heaviness were significantly longer before and after the visual task with tablet candy ( = 0.013 and = 0.025, respectively) but not with chewing gum. The changes of subjective accommodation were significantly lower after the visual task between chewing gum and candy ( = 0.043). There were significant differences among each age group (20 s vs. 30 s, = 0.594; 20 s vs. 40 s, = 0.002; 20 s vs. 50 s, = 0.002). After reading, the changes of spherical equivalent refraction did not indicate a shift toward myopia ( = 0.267). In the RBUT, there were no significant differences between the samples ( = 0.680).
Chewing gum helps improve the ability of the eye to focus, especially in young adults.
研究咀嚼口香糖和含服糖片对减轻健康人群视疲劳的效果。
本研究采用双盲交叉试验。共招募 46 名年龄在 20 至 59 岁之间、自觉眼疲劳的健康个体（男性 23 名，女性 23 名）。除 30 岁组包括 10 名个体外，其余每个 10 岁年龄组各包括 12 名个体。参与者在距离固定的电脑屏幕上阅读材料，阅读 60 分钟。阅读开始后 15 分钟和 45 分钟时，分别咀嚼两片口香糖或糖片，各持续 15 分钟。第一天咀嚼口香糖，第二天咀嚼糖片，以此类推。主要结局指标是视觉模拟量表（VAS）评估的主观眼疲劳（眼疲劳、眼沉重、视力模糊、复视和眼干）。次要结局指标是使用 D'ACOMO 测量的近点和远点调节的主观调节力、球镜等效折射和使用 RT-7000 Auto Ref-Topographer 测量的眨眼反射时间（RBUT）评估的眼干。
咀嚼口香糖和含服糖片后的 VAS 评分的主观眼疲劳无显著差异（ = 0.397， = 0.909）。咀嚼糖片后眼疲劳和眼沉重的评分在视觉任务前后显著延长（ = 0.013 和 = 0.025），但咀嚼口香糖无此变化。视觉任务后咀嚼口香糖和糖片的主观调节力变化差异有统计学意义（ = 0.043）。各年龄组之间存在显著差异（20 岁组与 30 岁组， = 0.594；20 岁组与 40 岁组， = 0.002；20 岁组与 50 岁组， = 0.002）。阅读后，球镜等效折射的变化并未提示近视倾向（ = 0.267）。在 RBUT 中，两组样本之间无显著差异（ = 0.680）。
咀嚼口香糖有助于提高眼睛的聚焦能力，尤其是在年轻成年人中。
