Vrije Universiteit Brussel, Department of Art, Sciences, and Archaeology, Maritime Cultures Research Institute, Belgium; Leiden University, Faculty of Archaeology, Human Osteology Laboratory, the Netherlands.
McMaster University, Faculty of Social Sciences, Department of Anthropology, Canada.
Int J Paleopathol. 2021 Mar;32:41-49. doi: 10.1016/j.ijpp.2020.10.010. Epub 2020 Dec 1.
By applying a joint medico-historical and paleopathological perspective, this paper aims to improve our understanding of factors influencing past vitamin D deficiency in ten Dutch 17th to 19th-century communities of varying socioeconomic status and settlement type.
Vitamin D deficiency is evaluated in 733 individuals of both sexes and all age groups: Silvolde (n = 16), Rotterdam (n = 23), Rhenen (n = 24), Noordwijkerhout (n = 27), Gouda1and 2 (n = 40; n = 59), Roosendaal (n = 51), Den Haag (n = 93), Hattem (n = 113), and Beemster (n = 287).
Rickets and residual rickets are macroscopically assessed using established criteria. Hypotheses formulated based on medico-historical texts are investigated via multivariate statistical analysis of vitamin D deficiency prevalence.
Vitamin D deficiency prevalence ranges from 13.7 % (7/51) in Roosendaal to 48.1 % (13/27) in Noordwijkerhout, with an onset of < 4 years, and higher rates in cities, conforming to medico-historical texts. Patterns of child labor are likely key. In contrast, socioeconomic status did not statistically significantly influence vitamin D deficiency prevalence rates.
Systematically collected paleopathological data enabled evaluation of medico-historical texts and provided insights into the role that socioeconomic status and settlement type played on the prevalence of vitamin D deficiency.
Combining medico-historical texts and large-scale paleopathological data enables disease patterning to be embedded in a comprehensive biocultural perspective.
Comparisons may be limited by the small sample size of high socioeconomic status nonadults and some of the collections.
Analysis of more individuals and sites would improve our understanding of disease patterns.
通过应用医学历史和古病理学的联合视角，本文旨在增进我们对过去维生素 D 缺乏影响因素的理解，这些因素涉及到荷兰 17 至 19 世纪不同社会经济地位和定居类型的 10 个社区。
评估了来自 Silvolde（n = 16）、鹿特丹（n = 23）、Rhenen（n = 24）、Noordwijkerhout（n = 27）、Gouda1 和 2（n = 40；n = 59）、Roosendaal（n = 51）、海牙（n = 93）、Hattem（n = 113）和 Beemster（n = 287）的 733 名不同性别和各年龄段个体的维生素 D 缺乏情况：佝偻病和残余性佝偻病使用既定标准进行宏观评估。基于医学历史文本提出的假设通过维生素 D 缺乏流行率的多元统计分析进行检验。
维生素 D 缺乏的流行率范围从 Roosendaal 的 13.7%（7/51）到 Noordwijkerhout 的 48.1%（13/27），发病年龄<4 岁，城市中的发病率更高，这与医学历史文本相符。儿童劳动力模式可能是关键。相比之下，社会经济地位并没有显著影响维生素 D 缺乏的流行率。
系统收集的古病理学数据使我们能够评估医学历史文本，并深入了解社会经济地位和定居类型在维生素 D 缺乏症流行率中的作用。
将医学历史文本与大规模古病理学数据相结合，使疾病模式能够嵌入全面的生物文化视角中。
比较可能受到高社会经济地位非成年人和一些样本数量较小的限制。
分析更多的个体和地点将有助于我们更好地了解疾病模式。
