Laboratorio di Antropologia fisica, Dipartimento di Scienze Biologiche, Geologiche ed Ambientali, BiGeA, Università di Bologna, Bologna, Italy; Chaire d'Anthropologie biologique Paul Broca, EPHE-PSL University, Paris, France.
Chaire d'Anthropologie biologique Paul Broca, EPHE-PSL University, Paris, France; UMR 5199 PACEA, CNRS/University of Bordeaux/Ministry of Culture, LabEx Sciences archéologiques de Bordeaux, n°ANR-10-LABX-52, Pessac, France; Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.
Int J Paleopathol. 2021 Sep;34:76-81. doi: 10.1016/j.ijpp.2021.06.005. Epub 2021 Jun 29.
This study explores whether data relating to rickets from the French medico-historical literature (FMHL) and bioarchaeological grey literature are useful in evaluating its epidemiology during the industrialisation of France. Unlike other European countries such as England, industrialisation in France was a slow and continuous process with two phases: the first in 1830-1870 and the second in 1870-1914.
A bibliographical analysis of 2800 FMHL sources from the 18th to the early 20th centuries and 50 archaeological excavation reports from the last 21 years was undertaken.
The FMHL data is very heterogeneous and predominantly dates to the second phase of industrialisation. The bioarchaeological data is very incomplete and predominantly relates to the period before industrialisation. At the same time, knowledge improvement and institutional changes to protect children could explain more systematic registration of cases of rickets.
No solid conclusions can be made regarding the prevalence of rickets at present, however these data hold great potential.
In comparison to England, no systematic investigation of rickets prevalence during the period of industrialisation in France has been undertaken to date.
The lack of archaeological excavations from this period and the limited paleopathological analysis of the sites excavated have contributed to our current lack of understanding regarding the impact of industrialization on the prevalence of rickets on the French population.
The FMHL data needs to be homogenized and osteoarchaeological collections need to be restudied with a common protocol focusing on signs of vitamin D deficiency.
本研究旨在探讨法国医史学文献（FMHL）和生物考古学灰色文献中有关佝偻病的数据，是否有助于评估法国工业化时期佝偻病的流行病学情况。与其他欧洲国家（如英国）不同，法国的工业化是一个缓慢而持续的过程，分为两个阶段：第一阶段是 1830-1870 年，第二阶段是 1870-1914 年。
对 18 世纪至 20 世纪初的 2800 份 FMHL 文献和过去 21 年的 50 份考古发掘报告进行了文献分析。
FMHL 数据非常多样化，主要集中在工业化的第二阶段。生物考古学数据非常不完整，主要与工业化前时期有关。同时，知识的提高和保护儿童的制度变化，可以解释佝偻病病例更系统的登记。
目前，关于佝偻病的流行率，还不能得出确凿的结论，但这些数据具有很大的潜力。
与英国相比，目前尚未对法国工业化时期佝偻病的流行率进行系统调查。
该时期缺乏考古发掘，以及对已发掘遗址的有限古病理学分析，导致我们目前对工业化对法国人口佝偻病流行率的影响缺乏了解。
需要对 FMHL 数据进行同质化处理，并用一个共同的方案重新研究骨骼考古学收藏，重点研究维生素 D 缺乏的迹象。
