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癌症相关血栓形成的流行病学及危险因素

Epidemiology and risk factors for cancer-associated thrombosis.

作者信息

Sevestre M A, Soudet S

机构信息

Service de médecine Vasculaire - EA 7516 Chimère UPJV, CHU Amiens, 80064 Amiens cedex.

Service de médecine Vasculaire - EA 7516 Chimère UPJV, CHU Amiens, 80064 Amiens cedex.

出版信息

J Med Vasc. 2020 Nov;45(6S):6S3-6S7. doi: 10.1016/S2542-4513(20)30513-7.

DOI:10.1016/S2542-4513(20)30513-7
PMID:33276941
Abstract

Cancer associated thrombosis (CAT) has been demonstrated a long time ago and is a frequent comorbid condition. Some risk factors are well established and related to the treatment of cancer: surgery, chemotherapy, radiation therapy, indwelling catheters. Other risk factors depend on tumour type and patient presentation, in particular pancreatic and brain cancer, bed resting and previous venous thrombosis. With the advances in cancer treatment and care, patients with cancer live longer and experience various therapies, sometimes during a long time. There is a need to better define the incidence and prevalence of CAT in the light of new therapeutic strategies and patient survival. This article focuses on the description of incidence and prevalence of CAT in the literature and on the description of risk factors, traditional but also emerging ones.

摘要

癌症相关血栓形成(CAT)早在很久以前就已被证实,是一种常见的合并症。一些危险因素已明确确立,且与癌症治疗相关:手术、化疗、放疗、留置导管。其他危险因素则取决于肿瘤类型和患者表现,特别是胰腺癌和脑癌、卧床休息以及既往静脉血栓形成。随着癌症治疗和护理的进展,癌症患者寿命延长,会经历各种治疗,有时持续很长时间。鉴于新的治疗策略和患者生存率,有必要更好地界定CAT的发病率和患病率。本文重点描述文献中CAT的发病率和患病率,以及传统和新出现的危险因素。

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