Program in Cellular and Molecular Medicine, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.
Sci Immunol. 2020 Dec 4;5(54). doi: 10.1126/sciimmunol.abf0905.
Coral gasdermin E is cleaved by activated caspase-3 to induce pyroptosis, a form of inflammatory programmed cell death, in response to a bacterial pathogen (see the related Research Article by Jiang .).
珊瑚气胀素 E 被激活的 caspase-3 切割,以响应细菌病原体诱导细胞焦亡,这是一种炎症程序性细胞死亡形式(见 Jiang 的相关研究文章)。