Iribhogbe Osede Ignis, Odoya Ebube Manfred
Department of Pharmacology & Therapeutics, Faculty of Basic Clinical Sciences, College of Medicine, Ambrose Alli University, Ekpoma, Edo State, Nigeria.
Department of Zoology, Faculty of Life Sciences, Ambrose Alli University, Ekpoma, Edo State, Nigeria.
Pharmacoepidemiol Drug Saf. 2021 Apr;30(4):435-444. doi: 10.1002/pds.5178. Epub 2020 Dec 15.
The majority of the population has inappropriate malaria treatment-seeking behavior and little is known about self-medication practice with antimalarials among postpartum mothers.
AIM & OBJECTIVES OF STUDY: The study, therefore, aims to determine the prevalence of self-treatment practice with antimalarials and identify factors that determine inappropriate treatment-seeking practice in this susceptible group.
The study is a cross-sectional study that was conducted using a purposive sampling technique. In the study, 150 respondents were administered questionnaires by one-on-one interviews, and results were presented as frequencies and proportions. A chi-square test was done to determine the association between independent categorical variables and the dependent variable.
In the study, 91 (60.7%) of the women claimed they did malaria screening tests in the laboratory/clinic before treatment, while only half of them sought professional care for treatment after the screening test. Additionally, most of the participants claimed they practice self-medication with antimalarials for themselves (64, 42.7%), and their newborn children (34, 22.7%). The experience of adverse effects (χ = 4.790, df = 1, p = .029) drug prescription by doctors (χ = 10.26, df = 1, p = .001) and the experience of malaria in the rainy season (χ = 4.86, df = 2, p = .027) was significantly related to receiving malaria treatment in the clinic/hospital.
The study has shown that the practice of self-medication and inappropriate malaria treatment behavior is common in postpartum women in rural settings hence public health intervention that will develop standardized self-treatment guidelines for uncomplicated malaria will be useful in promoting appropriate self-treatment practice in this population. Highlights Self-medication practice with antimalarials among postpartum mothers both for themselves and their newborn child was 42.7% and 22.7% respectively One of the reasons adduced for such practice is that malaria is expensive to treat (37, 24.7%) Artemether/lumefantrine combination was the most commonly used drug for treatment (75.3%), and most of the participants preferred parenteral medication (68%) to oral drugs The experience of adverse effects was significantly related to receiving treatment in the clinic/hospital Of the 60.7% of women who claimed they did malaria screening test, only half of them sought professional care after the test.
大多数人有不恰当的疟疾治疗寻求行为，而产后母亲使用抗疟药进行自我药疗的情况鲜为人知。
因此，本研究旨在确定使用抗疟药进行自我治疗的流行情况，并确定决定这一易感人群中不恰当治疗寻求行为的因素。
本研究是一项采用立意抽样技术进行的横断面研究。在研究中，通过一对一访谈对150名受访者进行问卷调查，结果以频率和比例呈现。进行卡方检验以确定独立分类变量与因变量之间的关联。
在本研究中，91名（60.7%）女性称她们在治疗前在实验室/诊所进行了疟疾筛查测试，但其中只有一半人在筛查测试后寻求专业治疗。此外，大多数参与者称他们自己（64人，42.7%）以及他们的新生儿（34人，22.7%）使用抗疟药进行自我药疗。不良反应经历（χ = 4.790，自由度 = 1，p = 0.029）、医生的药物处方（χ = 10.26，自由度 = 1，p = 0.001）以及雨季的疟疾经历（χ = 4.86，自由度 = 2，p = 0.027）与在诊所/医院接受疟疾治疗显著相关。
该研究表明，自我药疗和不恰当的疟疾治疗行为在农村地区的产后妇女中很常见，因此制定针对非复杂性疟疾的标准化自我治疗指南的公共卫生干预措施将有助于促进该人群的恰当自我治疗行为。要点：产后母亲为自己和新生儿使用抗疟药进行自我药疗的比例分别为42.7%和22.7%；这种行为的一个原因是疟疾治疗费用高昂（37人，24.7%）；蒿甲醚/本芴醇组合是最常用的治疗药物（75.3%），大多数参与者更喜欢注射用药（68%）而非口服药物；不良反应经历与在诊所/医院接受治疗显著相关；在声称进行了疟疾筛查测试的60.7%的女性中，只有一半人在测试后寻求专业护理。
