Muricazine, a new hydrazine derivative from L. with antioxidant, lipoxygenase and urease inhibitory activities.

L., an important member of family Ranunculaceae upon submission to phytochemical studies, led to the isolation of a novel natural hydrazine derivative, muricazine (). Chemical structure of the compound was established with the aid of advanced spectroscopic techniques. It was evaluated for antioxidant, lipoxygenase, and urease (jack-bean) inhibitory activities. Results suggested that compound could scavenge the DPPH free radical (42.1 ± 0.12 M) to a great extent as compared to the standard (40.6 ± 0.91 M). However, it showed moderate inhibitory potential against lipoxygenase (65.2 ± 0.45 M) and urease (54.8 ± 0.23 M) enzymes.