生长在阿尔及利亚东部的药用盐生植物法国柽柳（柽柳科）的美容潜力：光保护和抗氧化活性。

The Cosmetic Potential of The Medicinal Halophyte Tamarix Gallica L. (Tamaricaceae) Growing in The Eastern Part of Algeria: Photoprotective and Antioxidant Activities.

作者信息

Lefahal Mostefa, Makhloufi El-Hani, Trifa Warda, Ayad Radia, El Hattab Mohamed, Benahmed Merzoug, Keskin Merve, Akkal Salah

机构信息

Valorization of Natural Resources, Bioactive Molecules and Biological Analysis Unit, Department of Chemistry, University of Mentouri Constantine1, Constantine, Algeria.

Laboratory of Natural Products Chemistry and Biomolecules (LNPCBioM), University of Blida 1, Faculty of Sciences, Road of Soumaâ, P.O. Box 270, 09000 Blida, Algeria.

出版信息

Comb Chem High Throughput Screen. 2021;24(10):1671-1678. doi: 10.2174/1386207323666201204141541.

DOI:10.2174/1386207323666201204141541

PMID:33280589

Abstract

AIM AND OBJECTIVE

Currently, the use of ingredients from natural sources has gained great attention in the cosmetic field, especially for the development of new photoprotective formulations. Therefore, the present study aimed to evaluate the cosmetic potential of the crude methanol extract and the ethyl acetate fraction of the medicinal halophyte Tamarix gallica L. (Tg) growing in the area of Tebessa in the eastern part of Algeria, by assessing their phenolic and flavonoid contents, photoprotective and antioxidant activities.

METHODS

The research approach consisted of determining phenolic and flavonoid contents of aerial parts via Folin-Ciocalteu and aluminum chloride methods, respectively. The antioxidant activity was measured through two in vitro methods, DPPH radical scavenging activity and total antioxidant capacity test (TAC). The in vitro photoprotective effect was evaluated according to the parameter SPF (Sun Protection Factor) by using the UV spectroscopic method in the UV-B region (290-320 nm).

RESULTS

The methanol extract (Tg-MeOH) and ethyl acetate (Tg-EtOAc) fraction showed good antioxidant activity with IC values of 14.05±0.66, 27.58±1.98 μg/mL respectively in the DPPH test. Furthermore, both extracts displayed strong total antioxidant capacity (287.01±7.85, 246.7±1.12 mg AAE/g, respectively) in the TAC test. Both extracts exhibited high photoprotective activity, with sun protection factor (SPF) values 37.03±0.22 and 36.08±0.03. The antioxidant and photoprotective activities of these extracts were probably related to polyphenols content (190.27±0.74 mg AGE /g and 121.77±1.29 mg AGE /g, respectively) and flavonoids (78.75±0.06 mg QE /g and 58.67±1.19mg/g).

CONCLUSION

Our findings show that extracts of Tamarix gallica L. could be a promising source to be mixed as a natural sunscreen and antioxidant agents into photoprotective cosmetic formulations.

摘要

目的

目前，天然来源成分在化妆品领域备受关注，尤其是在新型光防护配方的开发方面。因此，本研究旨在通过评估药用盐生植物法国柽柳（Tamarix gallica L.，Tg）生长于阿尔及利亚东部泰贝萨地区的粗甲醇提取物和乙酸乙酯馏分的酚类和黄酮类含量、光防护及抗氧化活性，来评价其在化妆品方面的潜力。

方法

研究方法包括分别通过福林 - 西奥尔特法和氯化铝法测定地上部分的酚类和黄酮类含量。抗氧化活性通过两种体外方法测定，即DPPH自由基清除活性和总抗氧化能力测试（TAC）。体外光防护效果通过在UV - B区域（290 - 320 nm）使用紫外光谱法根据防晒系数（SPF）参数进行评估。

结果

甲醇提取物（Tg - MeOH）和乙酸乙酯（Tg - EtOAc）馏分在DPPH测试中显示出良好的抗氧化活性，IC值分别为14.05±0.66、27.58±1.98 μg/mL。此外，两种提取物在TAC测试中均表现出较强的总抗氧化能力（分别为287.01±7.85、246.7±1.12 mg AAE/g）。两种提取物均表现出高光防护活性，防晒系数（SPF）值分别为37.03±0.22和36.08±0.03。这些提取物的抗氧化和光防护活性可能与多酚含量（分别为190.27±0.74 mg AGE /g和121.77±1.29 mg AGE /g）和黄酮类（78.75±0.06 mg QE /g和58.67±1.19mg/g）有关。