Dmytrenko Ganna, Tana Lorena, Cachau María-Victoria, Bravo Martín, Gonzalez Silvina, Correa Fernando, Fernandez-Solari Javier, De Laurentiis Andrea
Centre of Pharmacological and Botanical Studies, CEFYBO-CONICET-UBA, School of Medicine, University of Buenos Aires, Argentina.
Physiology Dept., School of Dentistry, University of Buenos Aires, Argentina.
J Clin Exp Dent. 2020 Dec 1;12(12):e1201-e1205. doi: 10.4317/jced.56922. eCollection 2020 Dec.
Mucosal ulcerations are an oral complication that can often affect kidney transplant patients, mostly due to the effect of immunosuppression. It has been frequently reported drug-induced ulceration or lymphoproliferative disorders with buccal manifestations however, some unusual disorders should also be considered, such as fungal infections, viruses, as well as opportunistic infection by other microorganisms. Determining the etiology and differential diagnose from other causes of mouth ulcers is very important for the adequate treatment of said lesion. Dental health of patients should also be taken into the account prior to the transplant surgery, since periodontal pockets are the main niche of microbial reservoir. Moreover, mixed with oral microbiota, parasites such as can be found in the dental plaque of patients with periodontal disease. Particularly, are anaerobic motile-flagellated protozoa that can both induce tissue damage and exacerbate preexistent injuries in vaginal and oral mucosa. Parasitic infection in the oral cavity has not been well studied and it is thought to be underreported. In the present study we report the first case in literature of presence of as a potential etiological factor of the oral ulcerations of a kidney transplanted patient that remitted after antibiotic treatment. Immunosuppression, protozoan, buccal lesion, oral mucosa, kidney transplant.
黏膜溃疡是一种口腔并发症,常影响肾移植患者,主要是由于免疫抑制的作用。经常有药物性溃疡或伴有颊部表现的淋巴增殖性疾病的报道,然而,也应考虑一些不寻常的疾病,如真菌感染、病毒感染以及其他微生物的机会性感染。确定病因并与口腔溃疡的其他病因进行鉴别诊断对于充分治疗所述病变非常重要。在移植手术前也应考虑患者的口腔健康,因为牙周袋是微生物储存的主要场所。此外,在牙周病患者的牙菌斑中可发现与口腔微生物群混合的寄生虫,如 。特别是, 是厌氧的有鞭毛的原生动物,可导致组织损伤并加重阴道和口腔黏膜先前存在的损伤。口腔寄生虫感染尚未得到充分研究,据认为报告不足。在本研究中,我们报告了文献中首例 作为肾移植患者口腔溃疡潜在病因的病例,该病例在抗生素治疗后缓解。免疫抑制、原生动物、颊部病变、口腔黏膜、肾移植。 (注:原文中部分“ ”处内容缺失,无法准确完整翻译)