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手术治疗头颈部髓外浆细胞瘤的复发率和进展率较低：病例队列研究及文献综述

Surgery results in low relapse and progression rates in extramedullary plasmacytoma of the head and neck: A case cohort and review of the literature.

作者信息

Skerget Matevz, Dovsak Tadej, Kos Gregor, Zver Samo

机构信息

University Medical Centre Ljubljana.

Faculty of Medicine, University of Ljubljana.

出版信息

Hematol Rep. 2020 Nov 17;12(2):8396. doi: 10.4081/hr.2020.8396. eCollection 2020 Nov 16.

DOI:10.4081/hr.2020.8396
PMID:33282164
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7686853/
Abstract

Extramedullary plasmacytoma of the head and neck is a rare indolent neoplasm. Radiotherapy is often the preferred treatment option with excellent local control and survival. The risk of local recurrence or transformation to multiple myeloma is 10-30%. In our case-cohort, thorough, sensitive initial evaluation for disseminated clonal disease and the incorporation of surgery led to excellent results with no recurrences or systemic progression.

摘要

头颈部髓外浆细胞瘤是一种罕见的惰性肿瘤。放疗通常是首选的治疗方案，具有良好的局部控制和生存率。局部复发或转化为多发性骨髓瘤的风险为10% - 30%。在我们的病例队列中，对播散性克隆性疾病进行全面、敏感的初始评估并结合手术治疗，取得了极佳的效果，无复发或全身进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/294b/7686853/afe5edea0656/hr-12-2-8396-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/294b/7686853/afe5edea0656/hr-12-2-8396-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/294b/7686853/afe5edea0656/hr-12-2-8396-g001.jpg

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Maximizing the Clinical Benefit of Radiotherapy in Solitary Plasmacytoma: An International Multicenter Analysis.最大化孤立性浆细胞瘤放疗的临床获益：一项国际多中心分析
Cancers (Basel). 2020 Mar 13;12(3):676. doi: 10.3390/cancers12030676.
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Solitary Plasmacytoma Treated by Lenalidomide-Dexamethasone in Combination with Radiation Therapy: Clinical Outcomes.孤立性浆细胞瘤采用来那度胺-地塞米松联合放射治疗的疗效：临床结果。
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Radiation Therapy for Solitary Plasmacytoma and Multiple Myeloma: Guidelines From the International Lymphoma Radiation Oncology Group.
上颌骨浆细胞瘤：诊断与治疗挑战
Hematol Rep. 2024 Jan 4;16(1):22-31. doi: 10.3390/hematolrep16010003.
孤立性浆细胞瘤和多发性骨髓瘤的放射治疗：国际淋巴瘤放射肿瘤学组指南。
Int J Radiat Oncol Biol Phys. 2018 Jul 15;101(4):794-808. doi: 10.1016/j.ijrobp.2018.05.009. Epub 2018 Jun 20.
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Treatment approaches and outcomes in plasmacytomas: analysis using a national dataset.浆细胞瘤的治疗方法和结果：利用国家数据集进行分析。
Leukemia. 2018 Jun;32(6):1414-1420. doi: 10.1038/s41375-018-0099-8. Epub 2018 Mar 21.
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Long-Term Follow-up of Monoclonal Gammopathy of Undetermined Significance.意义未明的单克隆丙种球蛋白病的长期随访
N Engl J Med. 2018 Jan 18;378(3):241-249. doi: 10.1056/NEJMoa1709974.
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