Staromłyński Jakub, Kowalewski Mariusz, Sarnowski Wojciech, Smoczyński Radosław, Witkowska Anna, Bartczak Maciej, Drobiński Dominik, Wierzba Waldemar, Suwalski Piotr
Department of Cardiac Surgery, Central Clinical Hospital of the Ministry of Interior and Administration, Centre of Postgraduate Medical Education, Warsaw, Poland.
Thoracic Research Centre, Collegium Medicum, Nicolaus Copernicus University, Innovative Medical Forum, Bydgoszcz, Poland.
J Thorac Dis. 2020 Nov;12(11):6446-6457. doi: 10.21037/jtd-20-2165.
Minimally invasive aortic valve (AV) surgery has become widely accepted alternative to standard sternotomy. Despite possible reduction in morbidity, this approach is not routinely performed for aortic surgery. Current report aimed to demonstrate early and mid-term outcomes in patients undergoing minimally invasive aortic root- and ascending aorta-replacement with or without concomitant AV replacement (AVR).
Between 2011 and 2018, 167 selected low- and intermediate risk patients (mean age: 64.1±11.3; 70% men; EuroSCORE II 2.58±3.26) underwent minimally invasive aortic surgery. The "V" shaped partial upper sternotomy was performed through a 6-cm skin incision. Patients were divided into minimally invasive root reimplantation/replacement/remodelling (root RRR), supracoronary aorta replacements (SCAR) and SCAR+AVR. Kaplan-Meier estimates of survival were used.
Mean follow-up was 3.1 year (max 7.7 years). Of 167 patients, 82 (49%) underwent SCAR; 44 (26%) SCAR + AVR. Forty-one patients (25%) underwent minimally invasive root RRR. Average aortic diameter was 6.00±0.46 cm. The cardiopulmonary bypass and aortic cross-clamp time were 152.0±46.8 and 101.8±36.8 minutes. There was one conversion to sternotomy. Median intensive care unit stay was 2.0 (IQR: 1.0-3.0) days. Thirty-day mortality was 1%. Within investigated follow-up, there was one late reoperation due to aortic valve thrombosis; late survival was estimated at 95% without differences between types of surgery: hazard ratio, 0.81; 95% CI: 0.36-1.81; P=0.61.
Minimally invasive aortic surgery performed through "V" shaped partial upper sternotomy is feasible and safe in selected patients regardless of the extent of repair, from supracoronary aorta replacements to complex root surgery.
微创主动脉瓣手术已成为标准胸骨切开术广泛接受的替代方案。尽管可能降低发病率,但这种方法在主动脉手术中并非常规应用。本报告旨在展示接受微创主动脉根部和升主动脉置换术(伴或不伴主动脉瓣置换术)患者的早期和中期结果。
2011年至2018年期间,167例选定的低风险和中等风险患者(平均年龄:64.1±11.3岁;70%为男性;欧洲心脏手术风险评估系统II评分为2.58±3.26)接受了微创主动脉手术。通过6厘米的皮肤切口进行“V”形部分上胸骨切开术。患者分为微创根部再植入/置换/重塑(根部RRR)、冠状动脉上主动脉置换(SCAR)和SCAR+主动脉瓣置换(AVR)。采用Kaplan-Meier法估计生存率。
平均随访3.1年(最长7.7年)。167例患者中,82例(49%)接受了SCAR手术;44例(26%)接受了SCAR+AVR手术。41例患者(25%)接受了微创根部RRR手术。平均主动脉直径为6.00±0.46厘米。体外循环和主动脉阻断时间分别为152.0±46.8分钟和101.8±36.8分钟。有1例转为胸骨切开术。重症监护病房中位住院时间为2.0(四分位间距:1.0 - 3.0)天。30天死亡率为1%。在研究的随访期内,有1例因主动脉瓣血栓形成进行了晚期再次手术;晚期生存率估计为95%,不同手术类型之间无差异:风险比为0.81;95%置信区间:0.36 - 1.81;P = 0.61。
通过“V”形部分上胸骨切开术进行的微创主动脉手术在选定患者中是可行且安全的,无论修复范围如何,从冠状动脉上主动脉置换到复杂的根部手术。