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大卫手术微创入路的中期结果

Midterm Results of a Minimally Invasive Approach in David Procedure.

作者信息

Monsefi Nadejda, Risteski Petar, Miskovic Aleksandra, Moritz Anton, Zierer Andreas

机构信息

Department of Thoracic and Cardiovascular Surgery, University Hospital Frankfurt, Frankfurt, Germany.

Department of Thoracic and Cardiovascular Surgery, Heart Center Siegburg, Siegburg, Germany.

出版信息

Thorac Cardiovasc Surg. 2018 Jun;66(4):301-306. doi: 10.1055/s-0037-1603495. Epub 2017 Jun 5.

Abstract

BACKGROUND

The David procedure is a well-known technique in selected patients with aortic root pathology. A minimally invasive approach in heart surgery increases open interest.

METHODS

From 1991 to 2015, the David technique was performed in 296 patients in our unit. In 90 cases, operations were performed through partial upper sternotomy. The patient mean age was 57 ± 14 years in the minimally invasive group ( = 90) and 58 ± 14 years in the complete sternotomy group ( = 206;  = 0.2). The neosinus modification was performed in 80 patients (89%) in the minimally invasive group and in 79 patients (38%) in the complete sternotomy group ( < 0.01). Mean follow-up was 3 ± 2 years in the minimally invasive group and 8 ± 4 years in the complete sternotomy group.

RESULTS

Thirty-day mortality was zero in the minimally invasive group and was 3% ( = 6) in the complete sternotomy group ( = 0.1). The need for packed red blood cells was significantly lower in the minimally invasive group (1.6 ± 3 U) than in the complete sternotomy group (3.7 ± 6 U;  < 0.01). Thirty late deaths (2% per patient-year) were observed in the complete sternotomy group versus zero in the minimally invasive group ( < 0.01). One patient (0.5% per patient-year) in the minimally invasive group and 12 patients (0.8% per patient-year) in the complete sternotomy group required reoperation in the follow-up period ( = 0.05).

CONCLUSIONS

Minimally invasive David technique for patients with ascending aortic aneurysm and aortic valve insufficiency offers a good solution with low perioperative blood transfusion rate. Our midterm results show low valve-related complications and reoperation rate. However, long-term follow-up of the minimally invasive group is necessary.

摘要

背景

大卫手术是治疗特定主动脉根部病变患者的一种知名技术。心脏手术中的微创方法越来越受到关注。

方法

1991年至2015年,我们科室对296例患者实施了大卫手术。其中90例通过部分上胸骨切开术进行手术。微创组患者平均年龄为57±14岁(n = 90),全胸骨切开术组患者平均年龄为58±14岁(n = 206;P = 0.2)。微创组80例患者(89%)进行了新窦部改良,全胸骨切开术组79例患者(38%)进行了新窦部改良(P < 0.01)。微创组平均随访时间为3±2年,全胸骨切开术组为8±4年。

结果

微创组30天死亡率为零,全胸骨切开术组为3%(n = 6)(P = 0.1)。微创组浓缩红细胞需求量(1.6±3 U)显著低于全胸骨切开术组(3.7±6 U;P < 0.01)。全胸骨切开术组观察到30例晚期死亡(每年2%),而微创组为零(P < 0.01)。微创组1例患者(每年0.5%)和全胸骨切开术组12例患者(每年0.8%)在随访期间需要再次手术(P = 0.05)。

结论

对于升主动脉瘤合并主动脉瓣关闭不全患者,微创大卫手术提供了一种围手术期输血率低的良好解决方案。我们的中期结果显示瓣膜相关并发症和再次手术率较低。然而,微创组需要进行长期随访。

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