Alvarez William, Lai Li Han, Grant Shakira J, Sabath Daniel E, Dillon Jasjit
Tufts University. Former Resident, Department of Oral and Maxillofacial Surgery, University of Washington, Seattle, WA, USA.
Department of Oral and Maxillofacial Surgery, University of Washington, Seattle, WA, USA.
Oral Maxillofac Surg Cases. 2019 Sep;5(3). doi: 10.1016/j.omsc.2019.100113. Epub 2019 Jul 3.
Burkitt lymphoma (BL) is a highly aggressive, B cell non-Hodgkin lymphoma (NHL) that is rare outside Africa. We report a case of HIV-associated BL originating in the right maxillary sinus in a 31-year-old Hispanic male living in Washington, USA. We also highlight the diagnostic challenges in arriving at the diagnosis when the patient initially presented with a painless right facial swelling. Rapid diagnosis and treatment are critical because BL is one of the fastest-growing tumors. Treatment involves brief duration of high intensity chemotherapy and central nervous system prophylaxis. It is important for oral and maxillofacial surgeons to recognize this disease and understand the necessary steps to treat this aggressive tumor.
伯基特淋巴瘤（BL）是一种侵袭性很强的B细胞非霍奇金淋巴瘤（NHL），在非洲以外地区较为罕见。我们报告了一例起源于右上颌窦的HIV相关伯基特淋巴瘤病例，患者为一名居住在美国华盛顿的31岁西班牙裔男性。我们还强调了该患者最初表现为右侧面部无痛性肿胀时，在做出诊断过程中所面临的诊断挑战。快速诊断和治疗至关重要，因为伯基特淋巴瘤是生长最快的肿瘤之一。治疗包括短期高强度化疗及中枢神经系统预防。口腔颌面外科医生认识这种疾病并了解治疗这种侵袭性肿瘤的必要步骤非常重要。
