Dept. of Periodontology, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center for Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan 250012, China.
Dept. of Stomatology, People's Hospital of Rizhao, Rizhao 276800, China.
Hua Xi Kou Qiang Yi Xue Za Zhi. 2024 Oct 1;42(5):675-682. doi: 10.7518/hxkq.2024.2023432.
Burkitt lymphoma is a highly aggressive B-cell lymphoma and the fastest proliferating human malignant tumor. If the disease is found in the early stage, the patient could have a high possibility to be cured successfully, whereas the prognosis is poor in the late stage. Burkitt lymphoma can occur in children and adults, and it is categorized as local (Africa), sporadic, and immunodeficiency associated type. Sporadic Burkitt lymphoma mainly affects children and adolescents, and the most common initial sites are abdominal organs and lymph nodes. Sporadic Burkitt lymphoma manifested by initial oral and maxillofacial lesions is relatively rare. Here, a case of pediatric sporadic Burkitt lymphoma, with oral and maxillofacial lesions as the first symptoms, was reported. The patient was treated in the Department of Periodontology, Shandong University School and Hospital of Stomatology. After timely checkup was provided, the patient was transferred to another hospital and had good results. In this article, an incidence of Burkitt lymphoma, with oral and maxillofacial lesions as the first symptom, was reviewed to provide reference for oral clinicians to achieve early diagnosis and treatment of patients with Burkitt lymphoma with oral diseases and improve the success rate of treatment.
伯基特淋巴瘤是一种高度侵袭性的 B 细胞淋巴瘤,也是人类生长最快的恶性肿瘤。如果在早期发现该疾病,患者成功治愈的可能性很高,而晚期预后则较差。伯基特淋巴瘤可发生于儿童和成人,可分为地方性(非洲)、散发性和免疫缺陷相关性。散发性伯基特淋巴瘤主要影响儿童和青少年,最常见的初始部位是腹部器官和淋巴结。以口腔和颌面部病变为首发表现的散发性伯基特淋巴瘤较为少见。本文报道了 1 例以口腔颌面部病变为首发症状的儿童散发性伯基特淋巴瘤病例。该患者在山东大学口腔医院牙周科就诊,经及时检查后转至外院治疗,效果良好。本文复习了以口腔颌面部病变为首发症状的伯基特淋巴瘤的发病情况,为口腔临床医生对口腔疾病患者进行早期诊断和治疗伯基特淋巴瘤,提高治疗成功率提供参考。