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新冠病毒疾病(COVID-19)的心脏并发症:众多出版物,诸多不确定性。

The cardiac complications of COVID-19: many publications, multiple uncertainties.

作者信息

Al-Mohammad Abdallah, Partridge David G, Fent Graham, Watson Oliver, Lewis Nigel T, Storey Robert F, Makris Michael, Chico Timothy J

机构信息

Department of Infection, Immunity and Cardiovascular Diseases, University of Sheffield, Sheffield, UK.

Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.

出版信息

Vasc Biol. 2020 Oct 20;2(1):R105-R114. doi: 10.1530/VB-20-0009. eCollection 2020.

DOI:10.1530/VB-20-0009
PMID:33283157
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7709917/
Abstract

Since the first description of COVID-19 in December 2019, more than 63,000 publications have described its virology, clinical course, management, treatment and prevention. Most physicians are now encountering, or will soon encounter, patients with COVID-19 and must attempt to simultaneously assimilate this avalanche of information while managing an entirely novel disease with few guiding precedents. It is increasingly clear that, although primarily a respiratory illness, COVID-19 is associated with cardiovascular complications. However, the true incidence of direct cardiac complications remains unclear, as all complications thus far reported can also occur in patients without COVID-19. In this review, we briefly summarise and critically appraise the data on cardiac complications associated with COVID-19 and describe some cases from our own experience. We identify unresolved questions and highlight the many uncertainties in this developing field.

摘要

自2019年12月首次描述新型冠状病毒肺炎(COVID-19)以来,已有超过63000篇出版物描述了其病毒学、临床病程、管理、治疗和预防。现在,大多数医生正在接诊或即将接诊COVID-19患者,并且必须在管理一种几乎没有指导先例的全新疾病的同时,试图同步吸收这大量的信息。越来越明显的是,尽管COVID-19主要是一种呼吸系统疾病,但它与心血管并发症有关。然而,直接心脏并发症的真实发病率仍不清楚,因为迄今为止报道的所有并发症也可能发生在没有COVID-19的患者中。在这篇综述中,我们简要总结并批判性地评估了与COVID-19相关的心脏并发症的数据,并描述了我们自己经验中的一些病例。我们确定了尚未解决的问题,并强调了这个不断发展的领域中的许多不确定性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c81/7709917/82e86a4b24bd/VB-20-0009fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c81/7709917/bdaf638dd721/VB-20-0009fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c81/7709917/82e86a4b24bd/VB-20-0009fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c81/7709917/bdaf638dd721/VB-20-0009fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c81/7709917/82e86a4b24bd/VB-20-0009fig2.jpg

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Lancet Rheumatol. 2020 Jul;2(7):e437-e445. doi: 10.1016/S2665-9913(20)30121-1. Epub 2020 May 7.
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COVID-19 and cardiac arrhythmias.新型冠状病毒肺炎与心律失常。
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Cureus. 2020 Jun 13;12(6):e8599. doi: 10.7759/cureus.8599.
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The QT interval in patients with COVID-19 treated with hydroxychloroquine and azithromycin.接受羟氯喹和阿奇霉素治疗的新冠肺炎患者的QT间期。
Nat Med. 2020 Jun;26(6):808-809. doi: 10.1038/s41591-020-0888-2.
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