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经皮腔内血管成形术治疗可疑椎动脉残端综合征。

Percutaneous transluminal angioplasty for suspected vertebral artery stump syndrome.

机构信息

Department of Neurosurgery, Yokohama Shin Midori General Hospital, Kanagawa, Japan.

Department of Neurological Surgery, Nippon Medical School, Tokyo, Japan.

出版信息

Neuroradiol J. 2020 Dec;33(6):520-524. doi: 10.1177/1971400920939077.

Abstract

Vertebral artery stump syndrome is a rare disease associated with a posterior circulation stroke after vertebral artery origin occlusion. However, few reports have addressed its management. We herein present a case involving a patient with vertebral artery stump syndrome who underwent successful intravascular intervention. We also present a literature review of previous cases of this rare disease. The present case involved a 91-year-old man with acute onset of vertigo and disturbance of consciousness. Diffusion-weighted imaging showed an acute ischaemic stroke in the bilateral cerebellar hemispheres. Magnetic resonance angiography revealed left vertebral artery origin occlusion. Angiography detected a nearly occluded left vertebral artery site, with distal antegrade collateral flow via the deep cervical artery at the C6 level. We observed intravascular stasis at the proximal end of the left vertebral artery via the collateral flow. We performed percutaneous transluminal angioplasty towards the occluded left vertebral artery site. The flow from the left vertebral artery was significantly improved. This is the first report of percutaneous transluminal angioplasty performed for vertebral artery stump syndrome. Although vertebral artery stump syndrome has a high risk of recurrence and a poor prognosis, endovascular intervention showed a better outcome than pharmacotherapy in our patient. However, such cases are rare and further investigations are needed.

摘要

椎动脉残端综合征是一种罕见的疾病,与椎动脉起始部闭塞后引起的后循环卒中有关。然而,关于其治疗的报道较少。本文报道了 1 例成功进行血管内介入治疗的椎动脉残端综合征患者,并对该罕见疾病的既往病例进行了文献复习。本例为 91 岁男性,急性起病眩晕伴意识障碍。弥散加权成像显示双侧小脑半球急性缺血性卒中。磁共振血管造影显示左侧椎动脉起始部闭塞。血管造影显示左侧椎动脉近段几乎闭塞,通过 C6 水平的深部颈内动脉存在远端顺行侧支循环。通过侧支循环观察到左侧椎动脉近端有血管内停滞。我们对左侧椎动脉闭塞部位进行了经皮腔内血管成形术。左侧椎动脉的血流明显改善。这是首例报道经皮腔内血管成形术治疗椎动脉残端综合征。虽然椎动脉残端综合征有很高的复发风险和不良预后,但在我们的患者中,血管内介入治疗的效果优于药物治疗。然而,此类病例较为罕见,需要进一步研究。

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2
Vertebral Artery Stump Syndrome.椎动脉残端综合征
Intern Med. 2018 Mar 1;57(5):733-736. doi: 10.2169/internalmedicine.9317-17. Epub 2017 Nov 20.
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J Neurol Sci. 2013 Jan 15;324(1-2):74-9. doi: 10.1016/j.jns.2012.10.005. Epub 2012 Oct 27.
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