Barnett H J, Peerless S J, Kaufmann J C
Stroke. 1978 Sep-Oct;9(5):448-56. doi: 10.1161/01.str.9.5.448.
A series of 9 patients have experienced hemisphere and retinal ischemia at an interval after occlusion of appropriate internal carotid arteries. All had radiological evidence of a persisting proximal stump to the occluded artery and, in most, pathological evidence of thrombotic material attached to atheromatous lesions within the stump. Thromboembolism from the stump via the anastomotic supply through ipsilateral common and external carotid arteries is thought to be responsible for the ischemic events to the brain or retina despite absence of flow through the internal carotid artery. Seven of the 9 were treated by surgical excision or obliteration of the stump and, when indicated, common and external carotid endarterectomy. Turbulence in the stump contributed to progressive atherosclerotic changes and probably aggravated thrombogenesis in this location with subsequent embolization into the anastomotic arteries.
一系列9例患者在适当的颈内动脉闭塞后的一段时间内经历了半球和视网膜缺血。所有患者均有影像学证据表明闭塞动脉存在持续的近端残端,并且在大多数情况下,有病理证据表明血栓物质附着于残端内的动脉粥样硬化病变。尽管颈内动脉无血流,但来自残端的血栓栓塞通过同侧颈总动脉和颈外动脉的吻合供血被认为是导致脑或视网膜缺血事件的原因。9例患者中有7例接受了手术切除或闭塞残端治疗,必要时还进行了颈总动脉和颈外动脉内膜切除术。残端的血流紊乱导致了动脉粥样硬化的进展性变化,可能加重了该部位的血栓形成,随后栓塞进入吻合动脉。