过渡金属催化的烯丙基、炔丙基和丙二烯基环已二烯酮的不对称去对称化反应。
Asymmetric desymmetrization of alkene-, alkyne- and allene-tethered cyclohexadienones using transition metal catalysis.
机构信息
Molecular, Macromolecular Chemistry and Materials, ESPCI Paris, PSL University, 10 rue Vauquelin, 75005, Paris, France.
出版信息
Chem Soc Rev. 2021 Jan 7;50(1):658-666. doi: 10.1039/d0cs00666a. Epub 2020 Dec 7.
PMID:33283801
Abstract
This review is covering the recent development of catalytic asymmetric domino reactions for the desymmetrization of alkene-, alkyne- and allene-tethered cyclohexadienones using transition metals and chiral ligands. This desymmetrization has emerged as an important strategy for the rapid construction of complex molecular skeletons, such as fused-polycycles or spirocyclic compounds in controlling multiple stereogenic centers.
摘要
这篇综述涵盖了使用过渡金属和手性配体催化不对称多米诺反应，对烯丙基、炔丙基和丙二烯基环戊二烯酮进行去对称化的最新进展。这种去对称化已成为快速构建复杂分子骨架的重要策略，例如在控制多个立体中心的情况下构建稠合多环或螺环化合物。
Zotero 插件