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COVID-19 相关的有症状视网膜微血管病变:单个病例报告。

Symptomatic Retinal Microangiopathy in a Patient with Coronavirus Disease 2019 (COVID-19): Single Case Report.

机构信息

Ophthalmology Department, Hospital Universitario Ramon y Cajal, IRYCIS, Madrid, Spain.

出版信息

Ocul Immunol Inflamm. 2021 May 19;29(4):642-644. doi: 10.1080/09273948.2020.1852260. Epub 2020 Dec 7.

Abstract

Coronavirus Disease 2019 (COVID-19) can cause conjunctivitis in up to 31.6% of patients. Additionally, retinal findings compatible with retinal microvascular ischemia have also been associated with coronavirus disease in asymptomatic patients. We describe a case of bilateral retinal changes compatible with microangiopathy occurring during the late phase of COVID-19. A 50-year-old man with bilateral pneumonia and positive polymerase chain reaction for SARS-CoV-2 developed an arcuate visual field defect in his left eye. Funduscopy revealed multiple, bilateral cotton-wool spots without haemorraghes. OCT-angiography revealed multifocal areas of retinal microvascular ischemia in the superficial plexus, the largest of which corresponded to the arcuate scotoma observed in the automated perimetry. Visual field defects due to retinal microangiopathy can occur during the late phase of COVID-19. Vascular changes observed in the retina may mimic what may be happening in other, less-accessible organs.

摘要

新型冠状病毒病 2019(COVID-19)可导致多达 31.6%的患者出现结膜炎。此外,无症状患者的冠状病毒病也与视网膜微血管缺血的视网膜表现相关。我们描述了一例 COVID-19 晚期发生的双侧符合微血管病的视网膜改变。一名 50 岁男性,双侧肺炎,SARS-CoV-2 聚合酶链反应阳性,左眼出现弓形视野缺损。眼底检查显示双侧多发性棉絮斑,无出血。OCT-血管造影显示浅层丛多处视网膜微血管缺血区,其中最大的与自动视野计观察到的弓形暗点相对应。COVID-19 晚期可能出现视网膜微血管病引起的视野缺损。视网膜观察到的血管变化可能类似于其他不易触及的器官中可能发生的情况。

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