Department of Pathology, University of Miami, Miami, FL.
Department of Pathology, University of Colorado, Boulder, CO.
Am J Surg Pathol. 2022 Jan 1;46(1):e1-e14. doi: 10.1097/PAS.0000000000001637.
This review, based on the content of the 2020 US Gastrointestinal Pathology Society's Rodger Haggitt Lecture, concerns an array of tubular gastrointestinal tract dysplastic or possible "predysplastic lesions" with an almost purely morphologic focus based on our collaborative efforts over the past few years. These processes include esophageal epidermoid metaplasia, Barrett esophagus-associated dysplasia, polypoid gastric dysplastic lesions, small intestinal dysplasia, and the ability of metastases to mimic it, the controversial "serrated epithelial change" encountered in the setting of long-standing ulcerative and Crohn colitis, and recently described anal columnar human papilloma virus-associated neoplasms.
这篇综述基于 2020 年美国胃肠病学病理学学会罗格·哈格特讲座的内容,涉及一系列管状胃肠道发育不良或可能的“前发育性病变”,主要基于我们过去几年的合作努力,几乎完全侧重于形态学。这些过程包括食管表皮化生、 Barrett 食管相关异型增生、息肉状胃异型增生病变、小肠异型增生以及转移瘤的模拟能力、在长期溃疡性结肠炎和克罗恩病背景下遇到的有争议的“锯齿状上皮改变”,以及最近描述的肛门柱状人乳头瘤病毒相关肿瘤。