Thamizhanban Ayyapillai, Balaji Srikanth, Lalitha Krishnamoorthy, Prasad Yadavali Siva, Prasad R Vara, Kumar R Arun, Maheswari C Uma, Sridharan Vellaisamy, Nagarajan Subbiah
Department of Chemistry, School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur 613401, Tamil Nadu, India.
Department of Chemistry, National Institute of Technology Warangal, Warangal 506004, Telangana, India.
J Agric Food Chem. 2020 Dec 16;68(50):14896-14906. doi: 10.1021/acs.jafc.0c02936. Epub 2020 Dec 7.
Over the past few decades, the scientific community is actively involved in the development of edible structuring agents suitable for food, cosmetics, agricultural, pharmaceutical, and biotechnology applications. In particular, edible oil structuring using simple amphiphiles would be the best alternative for the currently used trans and saturated fatty acids, which cause deleterious health effects and cardiovascular problems. In this report, we have made an attempt to address the aforementioned consequences, by synthesizing a new class of structuring agents by a judicious combination of δ-gluconolactone and ricinoleic acid, compounds classified as GRAS, using simple steps in good yield. To our delight, the synthesized glycolipids self-assemble in a wide variety of vegetable oils and commercially viable glycerol, ethylene glycol, and polyethylene glycol via various intermolecular interactions to form a gel. The morphology of molecular gels was investigated by optical microscopy and FESEM analysis, which reveal the existence of a tubular architecture with a diameter ranging from 75 to 150 nm. Rheological studies disclosed the viscoelastic nature, thermal processability, and thixotropic behavior of both oleogels and organogels. Altogether, self-assembled oleogel and organogel reported in this paper would potentially be used in food, agricultural, cosmetics, pharmaceutical, and biotechnological applications.
在过去几十年里，科学界积极参与开发适用于食品、化妆品、农业、制药和生物技术应用的可食用结构剂。特别是，使用简单两亲分子进行食用油结构化将是目前使用的反式脂肪酸和饱和脂肪酸的最佳替代品，因为这些脂肪酸会对健康产生有害影响并引发心血管问题。在本报告中，我们试图通过将δ-葡萄糖酸内酯和蓖麻油酸（归类为GRAS的化合物）进行明智组合，采用简单步骤且高产率地合成一类新的结构剂，来解决上述问题。令我们高兴的是，合成的糖脂通过各种分子间相互作用在多种植物油以及具有商业可行性的甘油、乙二醇和聚乙二醇中自组装形成凝胶。通过光学显微镜和场发射扫描电子显微镜分析研究了分子凝胶的形态，结果表明存在直径范围为75至150 nm的管状结构。流变学研究揭示了油凝胶和有机凝胶的粘弹性性质、热加工性能和触变行为。总之，本文报道的自组装油凝胶和有机凝胶可能会用于食品、农业、化妆品、制药和生物技术应用。
