Singh Vandana, Thamizhanban Ayyapillai, Lalitha Krishnamoorthy, Subbiah Dinesh Kumar, Rachamalla Arun Kumar, Rebaka Vara Prasad, Banoo Tohira, Kumar Yogendra, Sridharan Vellaisamy, Ahmad Asrar, Maheswari Chockalingam Uma, Balaguru Rayappan John Bosco, Khan Azmat Ali, Nagarajan Subbiah
Department of Chemistry, School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur 613401, Tamil Nadu, India.
Centre for Nano Technology & Advanced Biomaterials (CeNTAB), School of Electrical & Electronics Engineering, SASTRA Deemed University, Thanjavur 613401, Tamil Nadu, India.
Gels. 2023 May 26;9(6):442. doi: 10.3390/gels9060442.
The inhalation, ingestion, and body absorption of noxious gases lead to severe tissue damage, ophthalmological issues, and neurodegenerative disorders; death may even occur when recognized too late. In particular, methanol gas present in traces can cause blindness, non-reversible organ failure, and even death. Even though ample materials are available for the detection of methanol in other alcoholic analogs at ppm level, their scope is very limited because of the use of either toxic or expensive raw materials or tedious fabrication procedures. In this paper, we report on a simple synthesis of fluorescent amphiphiles achieved using a starting material derived from renewable resources, this material being methyl ricinoleate in good yields. The newly synthesized bio-based amphiphiles were prone to form a gel in a broad range of solvents. The morphology of the gel and the molecular-level interaction involved in the self-assembly process were thoroughly investigated. Rheological studies were carried out to probe the stability, thermal processability, and thixotropic behavior. In order to evaluate the potential application of the self-assembled gel in the field of sensors, we performed sensor measurements. Interestingly, the twisted fibers derived from the molecular assembly could be able to display a stable and selective response towards methanol. We believe that the bottom-up assembled system holds great promise in the environmental, healthcare, medicine, and biological fields.
有害气体的吸入、摄入和身体吸收会导致严重的组织损伤、眼科问题和神经退行性疾病；如果认识过晚甚至可能导致死亡。特别是微量存在的甲醇气体会导致失明、不可逆的器官衰竭甚至死亡。尽管有大量材料可用于检测其他醇类类似物中ppm级别的甲醇，但由于使用有毒或昂贵的原材料或繁琐的制造程序，其范围非常有限。在本文中，我们报道了一种简单的荧光两亲物合成方法，该方法使用可再生资源衍生的起始材料，即蓖麻油酸甲酯，产率良好。新合成的生物基两亲物易于在广泛的溶剂中形成凝胶。对凝胶的形态和自组装过程中涉及的分子水平相互作用进行了深入研究。进行了流变学研究以探究稳定性、热加工性和触变性行为。为了评估自组装凝胶在传感器领域的潜在应用，我们进行了传感器测量。有趣的是，由分子组装得到的扭曲纤维能够对甲醇表现出稳定且选择性的响应。我们相信这种自下而上组装的系统在环境、医疗保健、医学和生物领域具有巨大的潜力。
