Department of Pharmacology, School of Medicine, Faculty of Health Sciences, University of the Free State, Bloemfontein 9300, South Africa.
Department of Pharmacology, School of Medicine, Faculty of Health Sciences, University of the Free State, Bloemfontein 9300, South Africa.
Transfus Clin Biol. 2021 Feb;28(1):123-127. doi: 10.1016/j.tracli.2020.11.004. Epub 2020 Dec 5.
Since December 2019, the human populations of the 195 global countries continue experiencing grave health and life threats due to the current COVID-19 pandemic. As a result of the novelty of the pathogen, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), at present there is lack of preventive as well as therapeutic options for treating and managing the infection. The use of ancient immunotherapeutic technique - the convalescent plasma (CP) therapy, may act as an immediate and available option to control the COVID-19 pandemic. This review provides a concept and understanding on the CP therapy, its potential to control SARS-CoV-2 pandemic. The CP therapy might act as an immediate saviour for society from the virus. Although the CP therapy has exert affirmative result against COVID-19 it has not been recommended for long time use in COVID-19 and this review gives support for its possible application.
自 2019 年 12 月以来，由于当前的 COVID-19 大流行，全球 195 个国家的人类继续面临严重的健康和生命威胁。由于病原体的新颖性，即严重急性呼吸系统综合症冠状病毒 2（SARS-CoV-2），目前缺乏治疗和管理感染的预防和治疗选择。使用古老的免疫治疗技术——恢复期血浆（CP）疗法，可能是控制 COVID-19 大流行的一种即时可行的选择。本综述提供了对 CP 疗法的概念和理解，以及它控制 SARS-CoV-2 大流行的潜力。CP 疗法可能是社会抵御该病毒的即时救星。尽管 CP 疗法对 COVID-19 有积极的效果，但它并没有被推荐用于 COVID-19 的长期使用，本综述为其可能的应用提供了支持。
