Department of Radiology, Bolzano Hospital, Bolzano, Italy.
Servizio Pneumologico Aziendale, Azienda Sanitaria dell'Alto Adige, Bolzano, Italy.
Respiration. 2021;100(2):145-153. doi: 10.1159/000512782. Epub 2020 Dec 7.
Coronavirus disease 2019 (COVID-19) is a pandemic overwhelming the health care systems worldwide. Lung ultrasound (LUS) use has been proposed to identify suspected COVID-19 patients and direct them to the isolation area in the emergency department (ED) or to discharge them for outpatient treatment.
Our aim was to retrospectively investigate the use of LUS in the ED to identify COVID-19 pneumonia (CP).
We performed a retrospective single-center study including all patients accessing the ED who underwent LUS examination for suspicion of COVID-19 during the initial outbreak. Demographics, clinical parameters, laboratory values, imaging features, and outcome variables were collected. The receiver operating characteristic (ROC) curve was used to evaluate diagnostic accuracy.
A total of 41% patients were COVID-19-positive; 67% of them were diagnosed with CP. The ROC curve of the LUS score showed an area under the curve of 0.837 (95% CI 0.75-0.92) and with a cutoff value ≥3 identified 28 of 31 patients with CP and 11 of 15 without (sensitivity 90%, 95% CI 74-97%; specificity 75%, 95% CI 56-76%). LUS in combination with nasopharyngeal swab has a sensitivity of 100% (95% CI 74-97%) and a specificity of 61% (95% CI 44-67%).
LUS is a promising technique for early identification of CP in patients who accessed the ED in an active epidemic time. The LUS score shows a sensitivity of 90% for CP, allowing to quickly direct patients with COVID-19 to the ED isolation area or to discharge them for outpatient treatment.
2019 年冠状病毒病(COVID-19)是一场席卷全球卫生保健系统的大流行。已经提出使用肺部超声(LUS)来识别疑似 COVID-19 患者,并将其引导到急诊科(ED)的隔离区或将其出院进行门诊治疗。
我们旨在回顾性研究 LUS 在 ED 中的使用,以识别 COVID-19 肺炎(CP)。
我们进行了一项回顾性单中心研究,包括在最初爆发期间因疑似 COVID-19 而接受 LUS 检查的所有进入 ED 的患者。收集人口统计学、临床参数、实验室值、影像学特征和结局变量。使用接收者操作特征(ROC)曲线评估诊断准确性。
共有 41%的患者 COVID-19 呈阳性;其中 67%被诊断为 CP。LUS 评分的 ROC 曲线显示曲线下面积为 0.837(95%CI 0.75-0.92),临界值≥3 可识别 28 例 CP 患者和 11 例非 CP 患者(敏感性 90%,95%CI 74-97%;特异性 75%,95%CI 56-76%)。LUS 联合鼻咽拭子的敏感性为 100%(95%CI 74-97%),特异性为 61%(95%CI 44-67%)。
LUS 是在流行期间快速识别 ED 中 CP 的有前途的技术。LUS 评分对 CP 的敏感性为 90%,可快速将 COVID-19 患者引导到 ED 隔离区或出院进行门诊治疗。