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使用低水平呼气末正压通气策略成功治疗一名新冠肺炎所致急性呼吸窘迫综合征的重症患者:一份符合CARE标准的病例报告。

Successful treatment of a critically ill patient with acute respiratory distress syndrome from COVID-19 using mechanical ventilation strategy with low levels of positive end-expiratory pressure: A CARE-compliant case report.

作者信息

Guo Wei-Guang, Fang Bin, Xian Yan-Shan, Yu Zhi-Hui, Zhou Li-Xin

机构信息

Department of Critical Care Medicine of Foshan first people's Hospital, Foshan, 528000, Guangdong Province, China.

出版信息

Medicine (Baltimore). 2020 Dec 4;99(49):e23160. doi: 10.1097/MD.0000000000023160.

Abstract

INTRODUCTION

Acute respiratory distress syndrome (ARDS) secondary to COVID-19 is different from the ARDS caused by other infections. Conventional mechanical ventilation strategies using high levels of PEEP may not be beneficial and can even be harmful to patient with ARDS from COVID-19. So the ventilation strategies should be adjusted in order to improve the pulmonary ventilation function and oxygenation status, and outcomes of the patient.

PATIENT CONCERNS

Herein, we present a 76-year-old male patient with ARDS secondary to COVID-19. We describe our experience with mechanical ventilation strategy and the changes in respiratory mechanics in the patient during treatment.

DIAGNOSIS

The patient had tested positive for coronavirus (COVID-19) in nucleic acid test. Chest CT showed multiple ground glass shadows in both lungs.

INTERVENTIONS

The patient received mechanical ventilation with low tidal volume and low PEEP.

OUTCOMES

After treatment, the patients condition, as well as oxygenation status was improved, and he tested negative for the coronavirus several times.

CONCLUSION

This case demonstrated that the low tidal volume with low levels of PEEP ventilation strategy may be more suitable for ARDS from COVID-19.

摘要

引言

新型冠状病毒肺炎(COVID-19)继发的急性呼吸窘迫综合征(ARDS)不同于其他感染所致的ARDS。采用高水平呼气末正压(PEEP)的传统机械通气策略可能并无益处,甚至可能对COVID-19所致ARDS患者有害。因此,应调整通气策略,以改善患者的肺通气功能、氧合状态及预后。

患者情况

在此,我们报告1例76岁男性COVID-19继发ARDS患者。我们描述了该患者机械通气策略及治疗期间呼吸力学变化的经验。

诊断

该患者核酸检测新型冠状病毒(COVID-19)呈阳性。胸部CT显示双肺多发磨玻璃影。

干预措施

该患者接受低潮气量、低PEEP机械通气。

结果

治疗后,患者病情及氧合状态改善,多次新型冠状病毒检测呈阴性。

结论

该病例表明,低潮气量、低水平PEEP通气策略可能更适用于COVID-19所致ARDS。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f89/7717814/8f844dfaebaa/medi-99-e23160-g001.jpg

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