益气活血方治疗缺血性脑卒中的疗效：一项回顾性研究。
Effect of Yiqihuoxue Formula for the treatment of ischemic stroke: A retrospective study.
作者信息
Ren Dong-Feng, Wang Ting, Sun Guo-Fang, Jiang Chao
机构信息
Department of Internal Medicine, The First Hospital of Yulin, Yulin, Shaanxi.
School of Economics and Management, Xidian University, Xi'an.
出版信息
Medicine (Baltimore). 2020 Dec 4;99(49):e23260. doi: 10.1097/MD.0000000000023260.
This retrospective study assessed the feasible effect of Yiqihuoxue Formula (YQHXF) for the treatment of patients with ischemic stroke (IS).A total of 66 patients with IS were included in this retrospective study. All patients received routine treatment, and were divided into two groups: a treatment group (n = 33) and a control group (n = 33). In addition to the routine treatment, all patients in the treatment group also underwent YQHXF treatment. All patients in both groups were treated for a total of 8 weeks. The outcomes were assessed by National Institute of Health Stroke Scale (NIHSS), modified Rankin scale (mRS), Barthel index scale (BIS), stroke-specific quality of life (SS-QOL) scale, and adverse events. All outcomes were measured before and after the treatment.After treatment, patients in the treatment group showed better improvements in NIHSS scale (P = .01), mRS (P < .01), BIS (P = .04), and SS-QOL scale (P = .04), than patients in the control group. No treatment-associated adverse events were recorded in this study.The results of this study indicated that YQHXF may benefit for patients with IS.
本回顾性研究评估了益气活血方（YQHXF）治疗缺血性脑卒中（IS）患者的可行性效果。本回顾性研究共纳入66例IS患者。所有患者均接受常规治疗，并分为两组：治疗组（n = 33）和对照组（n = 33）。治疗组所有患者除接受常规治疗外，还接受益气活血方治疗。两组所有患者均接受为期8周的治疗。通过美国国立卫生研究院卒中量表（NIHSS）、改良Rankin量表（mRS）、Barthel指数量表（BIS）、卒中特异性生活质量（SS-QOL）量表及不良事件评估疗效。所有疗效指标均在治疗前后进行测量。治疗后，治疗组患者在NIHSS量表（P = 0.01）、mRS（P < 0.01）、BIS（P = 0.04）和SS-QOL量表（P = 0.04）方面的改善均优于对照组。本研究未记录到与治疗相关的不良事件。本研究结果表明，益气活血方可能对IS患者有益。
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