Zhang Jue, Mei Liejun, Wang Fubing, Li Yan
Department of Peritoneal Cancer Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, PR. China.
Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan 430071, PR. China.
Medicine (Baltimore). 2020 Dec 4;99(49):e23404. doi: 10.1097/MD.0000000000023404.
One of the most distinctive features of epithelial ovarian cancer is tendency to disseminate into peritoneal cavity to form peritoneal carcinomatosis, indicating advanced disease with poor prognosis.
A fifty-year-old patient had a chief complaint of an abdominal distension lasting 1 month.
The patient was diagnosed with advanced epithelial ovarian cancer with peritoneal carcinomatosis by computed tomography scan, tumor markers, endoscopy examination, and pathology.
The patient was treated with cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy followed by 8 cycles of systemic chemotherapy.
Till March 9, 2020, the patient has disease-free survival over 10 years.
The application of cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy combined with systematic chemotherapy may improve survival dramatically for the patients with epithelial ovarian cancer and peritoneal carcinomatosis and should be considered as an option of a relatively new regime.
上皮性卵巢癌最显著的特征之一是易于扩散至腹腔形成腹膜癌转移，这表明疾病已进展至晚期，预后较差。
一名50岁患者的主要诉求是腹胀持续1个月。
通过计算机断层扫描、肿瘤标志物、内镜检查及病理检查，该患者被诊断为晚期上皮性卵巢癌伴腹膜癌转移。
该患者接受了肿瘤细胞减灭术加腹腔内热化疗，随后进行了8个周期的全身化疗。
截至2020年3月9日，该患者无病生存期超过10年。
肿瘤细胞减灭术加腹腔内热化疗联合全身化疗的应用可能会显著提高上皮性卵巢癌伴腹膜癌转移患者的生存率，应被视为一种相对新的治疗方案选择。
