Roussel B, Pinon J M, Birembaut P, Rullier J, Pennaforte F
Clinique de Pédiatrie et de Puériculture, American Memorial Hospital, Reims.
Arch Fr Pediatr. 1987 Nov;44(9):795-7.
The authors report the case of a 1 month-old infant presenting with congenital toxoplasmosis associated with nephrotic syndrome and microscopic hematuria. Percutaneous renal biopsy showed a diffuse mild increase in mesangial cells and matrix, but immunofluorescence was negative. Electron microscopy revealed the presence of extensive fusion of foot processes. A review of the nephropathy of congenital toxoplasmosis is presented. Outcome seems to be favorable under steroid therapy. The pathophysiology of nephropathy is discussed, as well as the relationships or coincidence between congenital toxoplasmosis and nephrotic syndrome.
作者报告了一例1个月大的婴儿，患有先天性弓形虫病，伴有肾病综合征和镜下血尿。经皮肾活检显示系膜细胞和基质弥漫性轻度增加，但免疫荧光检查为阴性。电子显微镜检查发现足突广泛融合。本文对先天性弓形虫病的肾病进行了综述。在类固醇治疗下，预后似乎良好。文中讨论了肾病的病理生理学，以及先天性弓形虫病与肾病综合征之间的关系或巧合。
