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心力衰竭心脏泵血功能评估新概念的临床及研究意义

Clinical and research implications of new concepts in the assessment of cardiac pumping performance in heart failure.

作者信息

Tan L B

机构信息

Department of Cardiovascular Medicine, University of Birmingham, East Birmingham Hospital.

出版信息

Cardiovasc Res. 1987 Aug;21(8):615-22. doi: 10.1093/cvr/21.8.615.

DOI:10.1093/cvr/21.8.615
PMID:3328649
Abstract

Every cardiac pump has its own maximum performance, which denotes its pumping capability. The difference between the performance in the resting state and that at maximum is called pumping reserve. Cardiac pumping performance is therefore best quantified by its hydraulic power output. Cardiac pumping capability is predictive of the ultimate prognosis of patients in severe heart failure whereas pumping reserve is a major determinant of exercise capacity. The therapeutic efficacy of cardiotonic drugs used in the treatment of ambulant heart failure patients should be evaluated with reference to the way they alter the relation between cardiac pumping reserve and exercise capacity.

摘要

每个心脏泵都有其自身的最大性能,这代表了它的泵血能力。静息状态下的性能与最大性能之间的差异称为泵血储备。因此,心脏泵血性能最好通过其水力功率输出进行量化。心脏泵血能力可预测重度心力衰竭患者的最终预后,而泵血储备是运动能力的主要决定因素。治疗门诊心力衰竭患者所用强心药物的疗效,应参照其改变心脏泵血储备与运动能力之间关系的方式来评估。

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