Department of Estomatology, Division of Periodontology, School of Dentistry, University of São Paulo, Brazil; Institute of Tropical Medicine of São Paulo, Faculty of Medicine, University of São Paulo, Brazil.
Med Hypotheses. 2021 Jan;146:110436. doi: 10.1016/j.mehy.2020.110436. Epub 2020 Nov 27.
Dental professionals work closely with patients and present an increased risk of person-to-person transmission of SARS-CoV-2. Moreover, the use of ultrasonic scalers, air-water syringes, and slow and high-speed handpieces, which are common in the dental office, generate spatter and aerosol. The use of preprocedural mouthrinses has been proposed to reduce the viral load in saliva and oropharyngeal tissues, thus decreasing viral load in dental aerosol. Although some mouthrinses demonstrates an antiviral effect, there is limited evidence about the clinical efficacy of any mouthrinse in the reduction of SARS-CoV-2 in the dental aerosol. We hypothesized that mouthrinses may reduce SARS-CoV-2 viral load in the oropharynx and its fluids reducing viral load in dental aerosol. The potential use of mouthrinses is discussed, along with proposal of in vitro and clinical studies, in order to evaluate this hypothesis. If this hypothesis holds true, dental professionals and patients may benefit from the routine use of preprocedural mouthrinses.
牙科专业人员与患者密切接触，增加了 SARS-CoV-2 人际传播的风险。此外，牙科诊室中常用的超声洁牙机、水气枪和低速和高速涡轮机，会产生飞沫和气溶胶。术前漱口已被提议用于减少唾液和口咽组织中的病毒载量，从而降低牙科气溶胶中的病毒载量。虽然一些漱口液显示出抗病毒作用，但关于任何漱口液在减少牙科气溶胶中 SARS-CoV-2 方面的临床疗效的证据有限。我们假设漱口液可能会降低口咽部位及其液体中的 SARS-CoV-2 病毒载量，从而降低牙科气溶胶中的病毒载量。本文讨论了漱口液的潜在用途，并提出了体外和临床研究的建议，以验证这一假设。如果这一假设成立，牙科专业人员和患者可能会受益于术前常规使用漱口液。
