Florida International University, Robert Stempel College of Public Health and Social Work, Global Health Consortium, United States.
Fay W. Boozman College of Public Health at the University of Arkansas for Medical Sciences (UAMS), United States.
Vaccine. 2021 Jan 8;39(2):317-323. doi: 10.1016/j.vaccine.2020.11.059. Epub 2020 Dec 4.
From 2006 to 2011 nearly 174,000 deaths were prevented in Latin America and the Caribbean through vaccination of children under five, which is widely attributed to the Expanded Program on Immunization (EPI). Despite near global adoption of EPI recommendations, vaccination coverage shows substantial variation across world regions. Causes for low immunizations within regions are multifaceted and include vaccination program costs. To date, publications regarding vaccine coverage across Latin America and the Caribbean are not readily available. This study aimed to: (1) compare vaccine coverage trends across nations within the region; and (2) assess whether national immunization program expenditures are correlated with vaccine coverage.
Coverage for nine vaccines were collected by nation using publicly available data from WHO. National immunization program expenditures for each country were collected from the World Bank Index. The proportion of countries achieving 90% coverage in the years 2013 and 2017 for each vaccine were compared. Pearson correlation coefficients were calculated to measure the relationship between financing variables and DTP3 coverage for 2017.
In 2017, fewer Latin American and Caribbean nations were able to achieve 90% vaccine coverage for five vaccines compared to 2013. Mostly weak to moderate positive relationships were found between national immunization program expenditures and DTP3 coverage for 2017. Excluding Haiti, a weak negative relationship was found between total government expenditure on vaccines per infant and DTP3 coverage for 2017. Countries across Latin America and the Caribbean were largely self-reliant in funding vaccine expenditures.
Fewer countries across Latin America and the Caribbean are currently achieving optimum national vaccine coverage and weak to moderate relationships between routine immunization and vaccine expenditures and coverage were observed. Additional factors contributing to national vaccine coverage should be concomitantly examined to implement strategies which optimize delivery of childhood immunizations.
2006 年至 2011 年,拉丁美洲和加勒比地区通过为五岁以下儿童接种疫苗,避免了近 17.4 万人死亡,这主要归功于扩大免疫规划(EPI)。尽管全球广泛采用了 EPI 建议,但疫苗接种覆盖率在世界各地区存在很大差异。造成区域内免疫接种率低的原因是多方面的,包括疫苗接种计划的成本。迄今为止,关于拉丁美洲和加勒比地区疫苗接种覆盖率的出版物并不容易获得。本研究旨在:(1)比较该地区各国疫苗接种覆盖率的趋势;(2)评估国家免疫规划支出是否与疫苗接种覆盖率相关。
使用世界卫生组织(WHO)提供的公开数据,按国家收集九种疫苗的覆盖率。从世界银行指数收集每个国家的国家免疫规划支出数据。比较 2013 年和 2017 年各国实现 90%覆盖率的国家比例。计算 2017 年融资变量与 DTP3 覆盖率之间的 Pearson 相关系数。
2017 年,与 2013 年相比,拉丁美洲和加勒比地区较少国家能够实现五种疫苗 90%的覆盖率。2017 年,国家免疫规划支出与 DTP3 覆盖率之间主要存在弱至中度的正相关关系。不包括海地,2017 年每婴儿总政府疫苗支出与 DTP3 覆盖率之间存在弱负相关关系。拉丁美洲和加勒比地区各国在疫苗支出方面主要依靠自身。
拉丁美洲和加勒比地区目前有较少的国家实现了最佳的国家疫苗覆盖率,并且观察到常规免疫与疫苗支出和覆盖率之间存在弱至中度的关系。应该同时检查其他因素对国家疫苗覆盖率的影响,以实施优化儿童免疫接种的战略。