使用 Jalview 进行生物序列比对。
Alignment of Biological Sequences with Jalview.
机构信息
University of Dundee, Dundee, Scotland, UK.
Synpromics Ltd., Edinburgh, Scotland, UK.
出版信息
Methods Mol Biol. 2021;2231:203-224. doi: 10.1007/978-1-0716-1036-7_13.
Abstract
In this chapter, we introduce core functionality of the Jalview interactive platform for the creation, analysis, and publication of multiple sequence alignments. A workflow is described based on Jalview's core functions: from data import to figure generation, including import of alignment reliability scores from T-Coffee and use of Jalview from the command line. The accompanying notes provide background information on the underlying methods and discuss additional options for working with Jalview to perform multiple sequence alignment, functional site analysis, and publication of alignments on the web.
摘要
在本章中，我们介绍 Jalview 交互式平台的核心功能，用于创建、分析和发布多序列比对。描述了一个基于 Jalview 核心功能的工作流程：从数据导入到图形生成，包括从 T-Coffee 导入对齐可靠性分数以及从命令行使用 Jalview。随附的说明提供了有关底层方法的背景信息，并讨论了使用 Jalview 执行多序列比对、功能位点分析和在网络上发布比对的其他选项。
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