Jalview Java序列比对编辑器。

The Jalview Java alignment editor.

作者信息

Clamp Michele, Cuff James, Searle Stephen M, Barton Geoffrey J

机构信息

The Wellcome Trust Sanger Institute, Hinxton, UK.

出版信息

Bioinformatics. 2004 Feb 12;20(3):426-7. doi: 10.1093/bioinformatics/btg430. Epub 2004 Jan 22.

DOI:10.1093/bioinformatics/btg430

PMID:14960472

Abstract

Multiple sequence alignment remains a crucial method for understanding the function of groups of related nucleic acid and protein sequences. However, it is known that automatic multiple sequence alignments can often be improved by manual editing. Therefore, tools are needed to view and edit multiple sequence alignments. Due to growth in the sequence databases, multiple sequence alignments can often be large and difficult to view efficiently. The Jalview Java alignment editor is presented here, which enables fast viewing and editing of large multiple sequence alignments.

摘要

多序列比对仍然是理解相关核酸和蛋白质序列组功能的关键方法。然而，众所周知，自动多序列比对通常可以通过手动编辑得到改进。因此，需要用于查看和编辑多序列比对的工具。由于序列数据库的增长，多序列比对通常可能很大且难以高效查看。本文介绍了Jalview Java比对编辑器，它能够快速查看和编辑大型多序列比对。