Department of Cardiovascular Disease, Peking University First Hospital.
Key Laboratory of Molecular Cardiovascular Sciences, Peking University, Ministry of Education, Xicheng, Beijing, China.
Blood Press Monit. 2021 Feb 1;26(1):60-64. doi: 10.1097/MBP.0000000000000506.
The inter-arm SBP difference (IASBPD) can serve as a predictor of cardiovascular disease (CVD). In this study, we aimed to determine the relationship between IASBPD and central blood pressure (CBP).
The study cohort comprised of 7842 eligible individuals. Their BPs were assessed simultaneously in both arms using an Omron BP-203RPEIII vascular profiler, and the IASBPD was measured as the absolute difference in these values (absolute value of left minus right). The CBP was noninvasively measured using an Omron HEM-9000AI device. Multivariate regression analysis was used to assess the association between the central SBP (cSBP) and the IASBPD.
An IASBPD of ≥10 mmHg was positively associated with the cSBP (β = 2.26; 95% confidence interval, 1.04-3.48; P < 0.001). The interaction test showed no significant interactions between the IASBPD and any of the assessed covariates (age group; sex; BMI; smoking status; heart rate group; the presence of hypertension, diabetes, or CVD; and antihypertensive drug use) when the cSBP was used as the outcome in the subgroup analysis.
The mechanism underlying the ability of the IASBPD to predict CVD may partly involve an increase in the CBP.
手臂间收缩压差值（IASBPD）可作为心血管疾病（CVD）的预测指标。本研究旨在确定 IASBPD 与中心血压（CBP）之间的关系。
研究队列包括 7842 名符合条件的个体。使用欧姆龙 BP-203RPEIII 血管轮廓仪同时测量双臂血压，IASBPD 为这些值的绝对值差（左减去右）。使用欧姆龙 HEM-9000AI 设备无创测量 CBP。采用多元回归分析评估 cSBP 与 IASBPD 之间的关系。
IASBPD≥10mmHg 与 cSBP 呈正相关（β=2.26；95%置信区间，1.04-3.48；P<0.001）。交互检验显示，在亚组分析中以 cSBP 为结局时，IASBPD 与任何评估的协变量（年龄组；性别；BMI；吸烟状况；心率组；高血压、糖尿病或 CVD 的存在；以及降压药物的使用）之间无显著交互作用。
IASBPD 预测 CVD 的机制部分可能涉及 CBP 的增加。
